Ion channels are vital for all living cells and organisms. In-vitro electrophysiological techniques (e.g. Patch-Clamp) are the gold standard to measure bioelectrical currents from single channels and cells. Unfortunately, most of the conventional in-vitro electrophysiological techniques require very costly and bulky equipment in addition to highly trained staff; hence, it is not affordable for many individual research groups.
The newly launched e-phac facility combines powerful in-vitro electrophysiology with image-based techniques in order to offer a comprehensive approach to study bioelectrical signaling in cells and tissues. In the future, the facility plans to extend their services towards high-throughput automated patch clamp, an essential platform to search for novel therapeutic approaches in the context of personalized medicine.
The facility is open to discussing new projects, and can be found at the Irchel Campus of UZH, Department of Molecular Life Sciences, room Y13 K52.