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Hypoxia Induces Renal Epithelial Injury and Activates Fibrotic Signaling Through Up-Regulation of Arginase-II. Liang, Xiujie; Potenza Duilio, Michele; Brenna, Andrea; Ma, Yiqiong; Ren, Zhilong; Cheng, Xin; Ming, Xiu-Fen; Yang, Zhihong. (2021). Frontiers in Physiology 12: 2-13

Aldosterone controls primary cilium length and cell size in renal collecting duct principal cells. Komarynets, Olga; Chassot, Alexandra; Bernabeu, Eva; Czogalla, Jan; Roth, Isabelle; Liaudet, Nicolas; Prodon, François; Loffing, Johannes; Feraille, Eric. (2020). FASEB J. 34(2): 2625-2640

An expert update on novel therapeutic targets for hyperphosphatemia in chronic kidney disease: preclinical and clinical innovations. Cozzolino, Mario; Ketteler, Markus; Wagner, Carsten Alexander. (2020). Expert Opin Ther Targets. 24(5): 477-488

Circular RNAs as non-invasive urinary biomarker of kidney diseases. Kölling, Malte and Lorenzen, Johan M.. (2020). Ann Transl Med.

Cre-mediated, loxP independent sequential recombination of a tripartite transcriptional stop cassette allows for partial read-through transcription. Bapst, Andreas M; Dahl, Sophie L; Knöpfel, Thomas; Wenger, Roland H. (2020). Biophys. Acta Gene Regul 1863(8): 194568

Crosslinkable polymeric contrast agent for high-resolution X-ray imaging of the vascular system. Le, Ngoc An; Kuo, Willy; Müller, Bert; Kurtcuoglu, Vartan; Spingler, Bernhard. (2020). ChemComm 56(44): 5885-5888

Dialysis initiation improves calcification propensity. Belen Ponte, Menno Pruijm, Andreas Pasch, Anne Dufey-Teso, Pierre-Yves Martin, Sophie de Seigneux. (2020). Nephrol Dial Transplant.

Diffusion magnetic resonance imaging detects an increase in interstitial fibrosis earlier than the decline of renal function. Lena Berchtold, Lindsey A Crowe, Iris Friedli, David Legouis, Solange Moll, Thomas de Perrot, Pierre-Yves Martin, Jean-Paul Vallée, Sophie de Seigneux. (2020). Nephrol Dial Transplant.

Expression of NaPi-IIb in rodent and human kidney and upregulation in a model of chronic kidney disease. Motta, Sarah E; Imenez Silva, Pedro Henrique; Daryadel, Arezoo; Haykir, Betül; Pastor-Arroyo, Eva Maria; Bettoni, Carla; Hernando, Nati; Wagner, Carsten A. (2020). Pflugers Arch. 472(4): 449-460

HIF hydroxylase inhibitors decrease cellular oxygen consumption depending on their selectivity. Sulser, Pascale; Pickel, Christina; Günter, Julia; Leissing, Thomas M; Crean, Daniel; Schofield, Christopher J; Wenger, Roland H; Scholz, Carsten C. (2020). FASEB J. 34(2): 2344-2358

Hypokalemia and the Prevalence of Primary Aldosteronism. Beuschlein, Felix; Gruber, Sven. (2020). Horm Metab Res 52(6): 347-356

Hypoxia sensing by hepatic stellate cells leads to VEGF-dependent angiogenesis and may contribute to accelerated liver regeneration. Dirscherl, Konstantin; Schläpfer, Martin; Roth Z’graggen, Birgit; Wenger, Roland H; Booy, Christa; Flury-Frei, Renata; Fatzer, Rita; Aloman, Costica; Bartosch, Birke; Parent, Romain; Kurtcuoglu, Vartan; de Zélicourt, Diane; Spahn, Donat R; Beck Schimmer, Beatrice; Schadde, Erik. (2020). Sci Rep. 10: 4392

Impact of superimposed nephrological care to guidelines-directed management by primary care physicians of patients with stable chronic kidney disease: a randomized controlled trial. Patrick Saudan, Belen Ponte, Nicola Marangon, Chantal Martinez, Lena Berchtold, David Jaques, Thomas Ernandez, Sophie de Seigneux, Sebastian Carballo, Thomas Perneger & Pierre-Yves Martin. (2020). BMC Nephrol. 21

Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Luciani, Alessandro; Schumann, Anke; Berquez, Marine; Chen, Zhiyong; Nieri, Daniela; Failli, Mario; Debaix, Huguette; Festa, Beatrice Paola; Tokonami, Natsuko; Raimondi, Andrea; Cremonesi, Alessio; Carrella, Diego; Forny, Patrick; Kölker, Stefan; Diomedi Camassei, Francesca; Diaz, Francisca; Moraes, Carlos T; Di Bernardo, Diego; Baumgartner, Matthias R; Devuyst, Olivier. (2020). Nat Commun. 11(1): 970

Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress. Vasiliki Delitsikou, George Jarad, Renuga Devi Rajaram, Frédérique Ino, Joseph M. Rutkowski, Ci‐Di Chen, Celio X. C. Santos, Philipp E. Scherer, Carmela R. Abraham, Ajay M. Shah, Eric Feraille, Jeffrey H. Miner, Sophie de Seigneux. (2020). FASEB J. 34: 2087-2104

Loss of sodium chloride co-transporter impairs the outgrowth of the renal distal convoluted tubule during renal development. Schnoz, Christina; Carrel, Monique; Loffing, Johannes. (2020). Nephrol Dial Transplant. 35(3): 411-432

MALAT1: a therapeutic candidate for a broad spectrum of vascular and cardiorenal complications. Puthanveetil, Prasanth; Gutschner, Tony; Lorenzen, Johan. (2020). Hypertens Res. 43: 372-379

Multiparametric imaging reveals that mitochondria rich intercalated cells in the kidney collecting duct have a very high glycolytic capacity. Ghazi, Susan; Bourgeois, Soline; Gomariz, Alvaro; Bugarski, Milica; Haenni, Dominik; Martins, Joana R; Nombela-Arrieta, César; Unwin, Robert J; Wagner, Carsten A; Hall, Andrew M; Craigie, Eilidh. (2020). FASEB 34(6): 8510-8525

Parathyroid Hormone and Plasma Phosphate Are Predictors of Soluble α-Klotho Levels in Adults of European Descent. Dhayat, Nasser A; Pruijm, Menno; Ponte, Belen; Ackermann, Daniel; Leichtle, Alexander Benedikt; Devuyst, Olivier; Ehret, Georg; Guessous, Idris; Pechère-Bertschi, Antoinette; Pastor, Johanne; Martin, Pierre-Yves; Burnier, Michel; Fiedler, Georg-Martin; Vogt, Bruno; Moe, Orson W; Bochud, Murielle; Fuster, Daniel G. (2020). J Clin Endocrinol Metab. 105(4): dgz232

Potassium channels in control of renal function. Imenez Silva, Pedro H; Wagner, Carsten A. (2020). Kidney Int. 97(2): 253-255

Rapid Cellular Perception of Gravitational Forces in Human Jurkat T Cells and Transduction Into Gene Expression Regulation. Thiel, Cora Sandra; Christoffel, Swantje; Tauber, Svantje; Vahlensieck, Christian; de Zélicourt, Diane; Layer, Liliana E; Lauber, Beatrice; Polzer, Jennifer; Ullrich, Oliver. (2020). Int J Mol Sci 21(2): 514

Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal myofiber function and survival. Chande, Sampada; Caballero, Daniel; Ho, Bryan B; Fetene, Jonathan; Serna, Juan; Pesta, Dominik; Nasiri, Ali; Jurczak, Michael; Chavkin, Nicholas W; Hernando, Nati; Giachelli, Cecilia M; Wagner, Carsten A; Zeiss, Caroline; Shulman, Gerald I; Bergwitz, Clemens. (2020). Sci Rep. 10(1): 3069

The Antioxidative Role of Cytoglobin in Podocytes: Implications for a Role in Chronic Kidney Disease. Randi, Elisa B; Vervaet, Benjamin; Tsachaki, Maria; Porto, Elena; Vermeylen, Stijn; Lindenmeyer, Maja T; Thuy, Le Thi Thanh; Cohen, Clemens D; Devuyst, Olivier; Kistler, Andreas D; Szabo, Csaba; Kawada, Norifumi; Hankeln, Thomas; Odermatt, Alex; Dewilde, Sylvia; Wenger, Roland H; Hoogewijs, David. (2020). Antioxid Redox Signal. 32(16): 1155-1171

The iron chelator Deferasirox causes severe mitochondrial swelling without depolarization due to a specific effect on inner membrane permeability. Gottwald, Esther M; Schuh, Claus D; Drücker, Patrick; Haenni, Dominik; Pearson, Adam; Ghazi, Susan; Bugarski, Milica; Polesel, Marcello; Duss, Michael; Landau, Ehud M; Kaech, Andres; Ziegler, Urs; Lundby, Anne K M; Lundby, Carsten; Dittrich, Petra S; Hall, Andrew M. (2020). Sci Rep 10(1): 1577

The KNOW-CKD study: evidence for a link between proteinuria and alterations of mineral metabolism. de Seigneux, Sophie. (2020). Nephrol Dial Transplant. 35(3): 382-385

The proton-activated ovarian cancer G protein-coupled receptor 1 (OGR1) is responsible for renal calcium loss during acidosis. Mohebbi, Nilufar; Benabbas, Chahira; Vidal, Solange; Daryadel, Arezoo; Bourgeois, Soline; Velic, Ana; Ludwig, Marie-Gabrielle; Seuwen, Klaus; Wagner, Carsten A. (2020). Kidney Int. 29(4): 313-324

Time-course of sodium transport along the nephron in nephrotic syndrome: The role of potassium. Dizin, Eva; Olivier, Valérie; Maire, Charline; Komarynets, Olga; Sassi, Ali; Roth, Isabelle; Loffing, Johannes; de Seigneux, Sophie; Maillard, Marc; Rutkowski, Joseph M; Edwards, Aurélie; Feraille, Eric. (2020). FASEB J. 34(2): 2408-2424

A case of drug induced proximal tubular dysfunction. Hall, Andrew; Unwinn, Robert. (2019). cJASN 14(9): 1384-1387

A catalog of genetic loci associated with kidney function from analyses of a million individuals. Wuttke, M., Li, Y., Li, M., Sieber, K. B., Feitosa, M. F., Gorski, M., Tin, A., et al.. (2019). Nat Genet.

A Model of Uric Acid Transport in the Rat Proximal Tubule. Edwards, Aurélie; Auberson, Muriel; Ramakrishnan, Suresh K; Bonny, Olivier. (2019). American journal of physiology. Renal physiology

A preliminary survey of practice patterns across several European kidney stone centers and a call for action in developing shared practice. Ferraro, Pietro Manuel; Arrabal-Polo, Miguel Ángel; Capasso, Giovambattista; Croppi, Emanuele; Cupisti, Adamasco; Ernandez, Thomas; Fuster, Daniel G; Galan, Juan Antonio; Grases, Felix; Hoorn, Ewout J; Knauf, Felix; Letavernier, Emmanuel; Mohebbi, Nilufar; Moochhala, Shabbir; Petkova, Kremena; Pozdzik, Agnieszka; Sayer, John; Seitz, Christian; Strazzullo, Pasquale; Trinchieri, Alberto; Vezzoli, Giuseppe; Vitale, Corrado; Vogt, Liffert; Unwin, Robert J; Bonny, Olivier; Gambaro, Giovanni. (2019). Urolithiasis

Associations of autozygosity with a broad range of human phenotypes. Clark, D.W., Okada, Y., Moore, K.H.S. et al.. (2019). Nat Commun. 10: 4957

Axial differences in endocytosis along the proximal tubule. Polesel, Marcello; Hall, Andrew M. (2019). American Journal of Physiology 317(6): F1526-F1530

Biogenesis and Function of Circular RNAs in Health and in Disease. Haddad, George and Lorenzen, Johan M.. (2019). Front Pharmacol. 10: 428

Circular RNAs in Urine of Kidney Transplant Patients with Acute T Cell-Mediated Allograft Rejection. Kölling, Malte; Haddad, George; Wegmann, Urs; Kistler, Andreas; Bosakova, Andrea; Seeger, Harald; Hübel, Kerstin; Haller, Hermann; Mueller, Thomas F; Wüthrich, Rudolf P; Lorenzen, Johan M. (2019). Clin Chem.

Clinical aspects of the phosphate transporters NaPi-IIa and NaPi-IIb: mutations and disease associations. Lederer, Eleanor; Wagner, Carsten A. (2019). Pflugers Archiv : European journal of physiology 471(1): 137-148

Clinical Pharmacology in HIV Therapy. Atta, Mohamed G; De Seigneux, Sophie; Lucas, Gregory M. (2019). Clinical journal of the American Society of Nephrology : CJASN 14(3): 435-444

Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion. Keppner, A., Maric, D., Sergi, C. et al.Keppner, A., Maric, D., Sergi, C. et al.. (2019). Sci Rep. 9: 19540

Distal and proximal hypoxia response elements cooperate to regulate organ-specific erythropoietin gene expression. Orlando, Ilaria M C; Lafleur, Véronique N; Storti, Federica; Spielmann, Patrick; Crowther, Lisa; Santambrogio, Sara; Schödel, Johannes; Hoogewijs, David; Mole, David R; Wenger, Roland H. (2019). Haematologica.

Elevated FGF23 and disordered renal mineral handling with reduced bone mineralization in chronically erythropoietin over-expressing transgenic mice. Daryadel, Arezoo; Natale, Luciano; Seebeck, Petra; Bettoni, Carla; Schnitzbauer, Udo; Gassmann, Max; Wagner, Carsten A. (2019). Sci Rep. 9(1): 14989

Fluid Dynamics in the HeartMate 3: Influence of the Artificial Pulse Feature and Residual Cardiac Pulsation. Wiegmann, Lena; Thamsen, Bente; de Zélicourt, Diane; Granegger, Marcus; Boës, Stefan; Schmid Daners, Marianne; Meboldt, Mirko; Kurtcuoglu, Vartan. (2019). Artificial organs 43(4): 363-376

Gene panel sequencing identifies a likely monogenic cause in 7% of 235 Pakistani families with nephrolithiasis. Amar, Ali; Majmundar, Amar J; Ullah, Ihsan; Afzal, Ayesha; Braun, Daniela A; Shril, Shirlee; Daga, Ankana; Jobst-Schwan, Tilman; Ahmad, Mumtaz; Sayer, John A; Gee, Heon Yung; Halbritter, Jan; Knöpfel, Thomas; Hernando, Nati; Werner, Andreas; Wagner, Carsten; Khaliq, Shagufta; Hildebrandt, Friedhelm. (2019). Human genetics 138(3): 211-219

Generation of renal Epo-producing cell lines by conditional gene tagging reveals rapid HIF-2 driven Epo kinetics, cell autonomous feedback regulation, and a telocyte phenotype. Imeri, Faik; Nolan, Karen A; Bapst, Andreas M; Santambrogio, Sara; Abreu-Rodríguez, Irene; Spielmann, Patrick; Pfundstein, Svende; Libertini, Silvana; Crowther, Lisa; Orlando, Ilaria M C; Dahl, Sophie L; Keodara, Anna; Kuo, Willy; Kurtcuoglu, Vartan; Scholz, Carsten C; Qi, Weihong; Hummler, Edith; Hoogewijs, David; Wenger, Roland H. (2019). Kidney international 95(2): 375-387

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Teumer, Alexander; Li, Yong; et al; Devuyst, Olivier. (2019). Nat Commun. 10(1): 4130

Hepsin-mediated Processing of Uromodulin is Crucial for Salt-sensitivity and Thick Ascending Limb Homeostasis. Olinger, Eric; Lake, Jennifer; Sheehan, Susan; Schiano, Guglielmo; Takata, Tomoaki; Tokonami, Natsuko; Debaix, Huguette; Consolato, Francesco; Rampoldi, Luca; Korstanje, Ron; Devuyst, Olivier. (2019). Sci Rep. 9: 12287

Identification of cell and disease specific microRNAs in glomerular pathologies. Müller-Deile, Janina; Dannenberg, Jan; Liu, Peidi; Lorenzen, Johan; Nyström, Jenny; Thum, Thomas; Schiffer, Mario. (2019). Journal of cellular and molecular medicine

Intestinal Response to Acute Intragastric and Intravenous Administration of Phosphate in Rats. Layunta, Elena; Pastor Arroyo, Eva Maria; Kägi, Larissa; Thomas, Linto; Levi, Moshe; Hernando, Nati; Wagner, Carsten A. (2019). Cell Physiol Biochem. 52(4): 838-849

Lack of Renal Tubular Glucocorticoid Receptor Decreases the Thiazide-Sensitive Na+/Cl- Cotransporter NCC and Transiently Affects Sodium Handling. Canonica J, Frateschi S, Boscardin E, Ebering A, Sergi C, Jäger Y, Peyrollaz T, Mérillat AM, Maillard M, Klusonova P, Odermatt A, Koesters R, Debonneville A, Staub O, Verouti SN, Hummler E.. (2019). Front Physiol. 10: 989

Mechanisms of phosphate transport. Levi, Moshe; Gratton, Enrico; Forster, Ian C; Hernando, Nati; Wagner, Carsten A; Biber, Juerg; Sorribas, Victor; Murer, Heini. (2019). Nat Rev Nephrol. 15(8): 482-500

MicroRNA expression studies: challenge of selecting reliable reference controls for data normalization. Madadi, Soheil; Schwarzenbach, Heidi; Lorenzen, Johan; Soleimani, Meysam. (2019). Cell Mol Life Sci. 76(18): 3497-3514

Molecular Pathophysiology of Acid-Base Disorders. Wagner, Carsten A.; Imenez Silva, Pedro H.; Bourgeois, Soline. (2019). Semin Nephrol. 39(4): 340-352

Nephrolithiasis secondary to inherited defects in the thick ascending loop of henle and connecting tubules. Faller, Nicolas; Dhayat, Nasser A; Fuster, Daniel G. (2019). Urolithiasis 47(1): 43-56

Nitric oxide protects against AKI by reprogramming metabolism. Martin, Pierre-Yves; de Seigneux, Sophie. (2019). Nature reviews. Nephrology 15(4): 195-196

Now a Nobel gas: Oxygen. Fandrey, Joachim; Schödel, Johannes; Eckardt, Kai-Uwe; Katschinski, Dörthe M; Wenger, Roland H. (2019). Pflugers Arch. 471: 1343-1358

Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1. Pickel, Christina; Günter, Julia; Ruiz-Serrano, Amalia; Spielmann, Patrick; Fabrizio, Jacqueline-Alba; Wolski, Witold; Peet, Daniel J; Wenger, Roland H; Scholz, Carsten C. (2019). Redox Biol.

Propagation of Plasma L-Phenylalanine Concentration Fluctuations to the Neurovascular Unit in Phenylketonuria: An in silico Study. Taslimifar, Mehdi; Buoso, Stefano; Verrey, Francois; Kurtcuoglu, Vartan. (2019). Front Physiol. 10: 360

Protein Phosphatase 1 Inhibitor-1 Mediates the cAMP-Dependent Stimulation of the Renal NaCl Cotransporter. Penton, David; Moser, Sandra; Wengi, Agnieszka; Czogalla, Jan; Rosenbaek, Lena Lindtoft; Rigendinger, Fritz; Faresse, Nourdine; Martins, Joana R; Fenton, Robert A; Loffing-Cueni, Dominique; Loffing, Johannes. (2019). Journal of the American Society of Nephrology : JASN

Reduced-order modeling of blood flow for noninvasive functional evaluation of coronary artery disease. Buoso, Stefano; Manzoni, Andrea; Alkadhi, Hatem; Plass, André; Quarteroni, Alfio; Kurtcuoglu, Vartan. (2019). Biomech Model Mechanobiol. 18(6): 1867-1881

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Tin, A., Marten, J., Halperin Kuhns, V.L. et al.. (2019). Nat Genet. 51: 1459-1474

Targeting Glycolysis in Proliferative Kidney Diseases. Ghazi, Susan; Polesel, Marcello;  Hall, Andrew. (2019). Am J Physiol Renal Physiol 317(6): F1531-F1535

The hypoxic kidney: pathogenesis and noncoding RNA-based therapeutic strategies. Haddad, George; Kölling, Malte; Lorenzen, Johan M. (2019). Swiss medical weekly 149: 14703

The neuronal oxygen-sensing pathway controls postnatal vascularization of the murine brain. Nasyrov, Emil; Nolan, Karen A; Wenger, Roland H; Marti, Hugo H; Kunze, Reiner. (2019). FASEB J. 33(11): 12812-12824

The Oxysterol Synthesising Enzyme CH25H Contributes to the Development of Intestinal Fibrosis. Raselli, T; Wyss, A; Gonzalez Alvarado, M N; Weder, B; Mamie, C; Spalinger, M R; Van Haaften, W T; Dijkstra, G; Sailer, A W; Imenez Silva, P H; Wagner, C A; Tosevski, V; Leibl, Sebastian; Scharl, M; Rogler, G; Hausmann, M; Misselwitz, B. (2019). J Crohns Colitis. 13(9): 1186-1200

The rhythm of healthy kidneys. Egli-Spichtig, Daniela; Wagner, Carsten A. (2019). Pflugers Arch.

The serine-threonine kinase PIM3 is an aldosterone-regulated protein in the distal nephron. Spirli, Alessia; Cheval, Lydie; Debonneville, Anne; Penton, David; Ronzaud, Caroline; Maillard, Marc; Doucet, Alain; Loffing, Johannes; Staub, Olivier. (2019). Physiol Rep. 7(15): e14177

The Urinary Excretion of Uromodulin is Regulated by the Potassium Channel ROMK. Schiano, Guglielmo; Glaudemans, Bob; Olinger, Eric; Goelz, Nadine; Müller, Michael; Loffing-Cueni, Dominique; Deschenes, Georges; Loffing, Johannes; Devuyst, Olivier. (2019). Sci Rep. 9: 19517

Transgenic zebrafish modeling low-molecular-weight proteinuria and lysosomal storage diseases. Chen, Zhiyong; Luciani, Alessandro; Mateos, José María; Barmettler, Gery; Giles, Rachel H; Neuhauss, Stephan C F; Devuyst, Olivier. (2019). Kidney Int. 97(6): 1150-1163

Tubular NOX4 expression decreases in chronic kidney disease but does not modify fibrosis evolution. de Seigneux, Sophie. (2019). Redox Biol. 26

Tumor necrosis factor stimulates fibroblast growth factor 23 levels in chronic kidney disease and non-renal inflammation. Egli-Spichtig, Daniela; Imenez Silva, Pedro Henrique; Glaudemans, Bob; Gehring, Nicole; Bettoni, Carla; Zhang, Martin Y H; Pastor-Arroyo, Eva M; Schönenberger, Désirée; Rajski, Michal; Hoogewijs, David; Knauf, Felix; Misselwitz, Benjamin; Frey-Wagner, Isabelle; Rogler, Gerhard; Ackermann, Daniel; Ponte, Belen; Pruijm, Menno; Leichtle, Alexander; Fiedler, Georg-Martin; Bochud, Murielle; Ballotta, Virginia; Hofmann, Sandra; Perwad, Farzana; Föller, Michael; Lang, Florian; Wenger, Roland H; Frew, Ian; Wagner, Carsten A. (2019). Kidney Int. 96(4): 890-905

The UMOD Locus: Insights into the Pathogenesis and Prognosis of Kidney Disease. Devuyst, Olivier; Pattaro, Cristian. (2018). Journal of the American Society of Nephrology : JASN 29(3): 713-726

De novo NAD+ synthesis enhances mitochondrial function and improves health. Katsyuba, Elena; Mottis, Adrienne; Zietak, Marika; De Franco, Francesca; van der Velpen, Vera; Gariani, Karim; Ryu, Dongryeol; Cialabrini, Lucia; Matilainen, Olli; Liscio, Paride; Giacchè, Nicola; Stokar-Regenscheit, Nadine; Legouis, David; de Seigneux, Sophie; Ivanisevic, Julijana; Raffaelli, Nadia; Schoonjans, Kristina; Pellicciari, Roberto; Auwerx, Johan. (2018). Nature 563(7731): 354-359

Redox‐Dependent Bone Alkaline Phosphatase Dysfunction Drives Part of the Complex Bone Phenotype in Mice Deficient for Memo1. Moor, Matthias B; Ramakrishnan, Suresh K; Legrand, Finola; Dolder, Silvia; Siegrist, Mark; Durussel, Fanny; Centeno, Gabriel; Firsov, Dmitri; Hynes, Nancy E; Hofstetter, Willy; Bonny, Olivier. (2018). JBMR plus 2(4): 195-205

A model of calcium transport and regulation in the proximal tubule. Edwards, Aurélie; Bonny, Olivier. (2018). American journal of physiology. Renal physiology 315(4): 942-953

Acidosis and Deafness in Patients with Recessive Mutations in FOXI1. Enerbäck, Sven; Nilsson, Daniel; Edwards, Noel; Heglind, Mikael; Alkanderi, Sumaya; Ashton, Emma; Deeb, Asma; Kokash, Feras E.B.; Bakhsh, Abdulrahim R.A.; van’t Hoff, William; Walsh, Stephen B.; D’Arco, Felice; Daryadel, Arezoo; Bourgeois, Soline; Wagner, Carsten A.; Kleta, Robert; Bockenhauer, Detlef; Sayer, John A.. (2018). Journal of the American Society of Nephrology : JASN 29(3): 1041-1048

Acute regulated expression of pendrin in human urinary exosomes. Pathare, Ganesh; Dhayat, Nasser; Mohebbi, Nilufar; Wagner, Carsten A.; Cheval, Lydie; Neuhaus, Thomas J.; Fuster, Daniel G.. (2018). Pflugers Archiv : European journal of physiology 470(2): 427-438

Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity. Liao, Wan-Hui; Suendermann, Claudia; Steuer, Andrea Eva; Pacheco Lopez, Gustavo; Odermatt, Alex; Faresse, Nourdine; Henneberg, Maciej; Langhans, Wolfgang. (2018). JCI insight 3(14)

Arginase-II activates mTORC1 through myosin-1b in vascular cell senescence and apoptosis. Yu, Yi; Xiong, Yuyan; Montani, Jean-Pierre; Yang, Zhihong; Ming, Xiu-Fen. (2018). Cell death & disease 9(3): 313

Changes in V-ATPase subunits of human urinary exosomes reflect the renal response to acute acid/alkali loading and the defects in distal renal tubular acidosis. Pathare, Ganesh; Dhayat, Nasser A.; Mohebbi, Nilufar; Wagner, Carsten A.; Bobulescu, Ion A.; Moe, Orson W.; Fuster, Daniel G.. (2018). Kidney international 93(4): 871-880

Circadian rhythms and the kidney. Firsov, Dmitri; Bonny, Olivier. (2018). Nature reviews. Nephrology 14(10): 626-635

Circadian variation of ticagrelor-induced platelet inhibition in healthy adulty. Fournier, Stephane; Guenat, Florine; Fournier, Anne; Alberio, Lorenzo; Bonny, Olivier; Bertaggia Calderara, Debora; Bardy, Daniel; Lauriers, Nathalie; Harbaoui, Brahim; Monney, Pierre; Pascale, Patrizio; Eeckhout, Eric; Muller, Olivier. (2018). European heart journal. Cardiovascular pharmacotherapy 4(3): 166-171

Claudins: a tale of interactions in the thick ascending limb. Olinger, Eric; Houillier, Pascal; Devuyst, Olivier. (2018). Kidney international 93(3): 535-537

Clinical, biochemical, and pathophysiological analysis of SLC34A1 mutations. Fearn, Amy; Allison, Benjamin; Rice, Sarah J; Edwards, Noel; Halbritter, Jan; Bourgeois, Soline; Pastor-Arroyo, Eva M; Hildebrandt, Friedhelm; Tasic, Velibor; Wagner, Carsten A; Hernando, Nati; Sayer, John A; Werner, Andreas. (2018). Physiological reports 6(12): 13715

Combined Structural and Functional Imaging of the Kidney Reveals Major Axial Differences in Proximal Tubule Endocytosis. Schuh, Claus D; Polesel, Marcello; Platonova, Evgenia; Haenni, Dominik; Gassama, Alkaly; Tokonami, Natsuko; Ghazi, Susan; Bugarski, Milica; Devuyst, Olivier; Ziegler, Urs; Hall, Andrew M. (2018). Journal of the American Society of Nephrology : JASN 29(11): 2696-2712

Cooperation of Antiporter LAT2/CD98hc with Uniporter TAT1 for Renal Reabsorption of Neutral Amino Acids. Vilches, Clara; Boiadjieva-Knöpfel, Emilia; Bodoy, Susanna; Camargo, Simone; López de Heredia, Miguel; Prat, Esther; Ormazabal, Aida; Artuch, Rafael; Zorzano, Antonio; Verrey, François; Nunes, Virginia; Palacín, Manuel. (2018). Journal of the American Society of Nephrology : JASN

Defective autophagy degradation and abnormal tight junction-associated signaling drive epithelial dysfunction in cystinosis. Luciani, Alessandro; Festa, Beatrice Paola; Chen, Zhiyong; Devuyst, Olivier. (2018). Autophagy 14(7): 1157-1159

Effects of the SGLT-2 Inhibitor Empagliflozin on Renal Tissue Oxygenation in Non-Diabetic Subjects: A Randomized, Double-Blind, Placebo-Controlled Study Protocol. Muller, Marie-Eve; Pruijm, Menno; Bonny, Olivier; Burnier, Michel; Zanchi, Anne. (2018). Advances in therapy 35(6): 875-885

ENaC Knockout. Boscardin, Emilie; Perrier, Romain; Sergi, Chloé; Maillard, Marc P.; Loffing, Johannes; Loffing-Cueni, Dominique; Koesters, Robert; Rossier, Bernard C.; Hummler, Edith. (2018). Journal of the American Society of Nephrology : JASN 29(3): 977-990

Erythropoietin stimulates fibroblast growth factor 23 (FGF23) in mice and men. Daryadel, Arezoo; Bettoni, Carla; Haider, Thomas; Imenez Silva, Pedro H; Schnitzbauer, Udo; Pastor-Arroyo, Eva Maria; Wenger, Roland H; Gassmann, Max; Wagner, Carsten A. (2018). Pflugers Archiv : European journal of physiology 470(10): 1569-1582

Functional Polarity of Microvascular Brain Endothelial Cells Supported by Neurovascular Unit Computational Model of Large Neutral Amino Acid Homeostasis. Taslimifar, Mehdi; Buoso, Stefano; Verrey, Francois; Kurtcuoglu, Vartan. (2018). Frontiers in physiology 9: 171

Genome-Wide Meta-Analysis Unravels Interactions between Magnesium Homeostasis and Metabolic Phenotypes. Corre, Tanguy; Arjona, Francisco J.; Hayward, Caroline et al. (2018). Journal of the American Society of Nephrology : JASN 29(1): 335-348

Human Mutations in SLC2A9 (Glut9) Affect Transport Capacity for Urate. Ruiz, Anne; Gautschi, Ivan; Schild, Laurent; Bonny, Olivier. (2018). Frontiers in physiology 9: 476

Hypoxia-induced long non-coding RNA Malat1 is dispensable for renal ischemia/reperfusion-injury. Kölling, Malte; Genschel, Celina; Kaucsar, Tamas; Hübner, Anika; Rong, Song; Schmitt, Roland; Sörensen-Zender, Inga; Haddad, George; Kistler, Andreas; Seeger, Harald; Kielstein, Jan T.; Fliser, Danilo; Haller, Hermann; Wüthrich, Rudolf; Zörnig, Martin; Thum, Thomas; Lorenzen, Johan. (2018). Scientific reports 8(1): 3438

Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney. Festa, Beatrice Paola; Chen, Zhiyong; Berquez, Marine; Debaix, Huguette; Tokonami, Natsuko; Prange, Jenny Ann; Hoek, Glenn van de; Alessio, Cremonesi; Raimondi, Andrea; Nevo, Nathalie; Giles, Rachel H.; Devuyst, Olivier; Luciani, Alessandro. (2018). Nature communications 9(1): 161

Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability. King, Andrew J; Siegel, Matthew; He, Ying; Nie, Baoming; Wang, Ji; Koo-McCoy, Samantha; Minassian, Natali A; Jafri, Qumber; Pan, Deng; Kohler, Jill; Kumaraswamy, Padmapriya; Kozuka, Kenji; Lewis, Jason G; Dragoli, Dean; Rosenbaum, David P; O'Neill, Debbie; Plain, Allein; Greasley, Peter J; Jönsson-Rylander, Ann-Cathrine; Karlsson, Daniel; Behrendt, Margareta; Strömstedt, Maria; Ryden-Bergsten, Tina; Knöpfel, Thomas; Pastor Arroyo, Eva M; Hernando, Nati; Marks, Joanne; Donowitz, Mark; Wagner, Carsten A; Alexander, R Todd; Caldwell, Jeremy S. (2018). Science translational medicine 10(456)

Intestinal Activation of pH-Sensing Receptor OGR1 [GPR68] Contributes to Fibrogenesis. Hutter, Senta; van Haaften, Wouter T; Hünerwadel, Anouk; Baebler, Katharina; Herfarth, Neel; Raselli, Tina; Mamie, Céline; Misselwitz, Benjamin; Rogler, Gerhard; Weder, Bruce; Dijkstra, Gerard; Meier, Chantal Florence; de Vallière, Cheryl; Weber, Achim; Imenez Silva, Pedro H; Wagner, Carsten A; Frey-Wagner, Isabelle; Ruiz, Pedro A; Hausmann, Martin. (2018). Journal of Crohn's & colitis 12(11): 1348-1358

Kidney Mass Reduction Leads to l-Arginine Metabolism-Dependent Blood Pressure Increase in Mice. Pillai, Samyuktha Muralidharan; Seebeck, Petra; Fingerhut, Ralph; Huang, Ji; Ming, Xiu‐Fen; Yang, Zhihong; Verrey, François. (2018). Journal of the American Heart Association 7(5)

Lipodystrophy Increases the Risk of CKD Development in HIV-Positive Patients in Switzerland: The LIPOKID Study. Bouatou, Yassine; Gayet Ageron, Angele; Bernasconi, Enos; Battegay, Manuel; Hoffmann, Matthias; Staehelin, Cornelia; Merz, Laurent; Kovari, Helen; Fux, Christoph; de Seigneux, Sophie; Calmy, Alexandra; Calmy, Alexandra. (2018). Kidney international reports 3(5): 1089-1099

Noncoding RNAs in acute kidney injury. Brandenburger, Timo; Salgado Somoza, Antonio; Devaux, Yvan; Lorenzen, Johan M. (2018). Kidney international 94(5): 870-881

NRF2 regulates the glutamine transporter Slc38a3 (SNAT3) in kidney in response to metabolic acidosis. Lister, Adam; Bourgeois, Soline; Imenez Silva, Pedro H.; Rubio-Aliaga, Isabel; Marbet, Philippe; Walsh, Joanne; Shelton, Luke M.; Keller, Bettina; Verrey, Francois; Devuyst, Olivier; Giesbertz, Pieter; Daniel, Hannelore; Goldring, Christopher E.; Copple, Ian M.; Wagner, Carsten A.; Odermatt, Alex. (2018). Scientific reports 8(1): 5629-5629

OCRL Deficiency Impairs Endolysosomal Function in a Humanized Mouse Model for Lowe Syndrome and Dent Disease. Festa, Beatrice Paola; Berquez, Marine; Gassama, Alkaly; Amrein, Irmgard; Ismail, Hesham M; Samardzija, Marijana; Staiano, Leopoldo; Luciani, Alessandro; Grimm, Christian; Nussbaum, Robert L; De Matteis, Maria Antonietta; Dorchies, Olivier M; Scapozza, Leonardo; Wolfer, David Paul; Devuyst, Olivier. (2018). Human molecular genetics

Phosphate Homeostasis, Inflammation and the Regulation of FGF-23. Lang, Florian; Leibrock, Christina; Pandyra, Aleksandra A; Stournaras, Christos; Wagner, Carsten A; Föller, Michael. (2018). Kidney & blood pressure research 43(6): 1742-1748

Potential benefits and harms of NADPH oxidase type 4 in the kidneys and cardiovascular system. Rajaram, Renuga; Dissard, Romain; Jaquet, Vincent; Seigneux, Sophie. (2018). Nephrology Dialysis Transplantation 34(4)

Red blood cell volume is not decreased in ESA-naive anemic chronic kidney disease patients. Lundby, Carsten; Ponte, Belen; Lundby, Anne-Kristine; Robach, Paul; de Seigneux, Sophie. (2018). Physiological reports 6(21): 13900

Redox‐Dependent Bone Alkaline Phosphatase Dysfunction Drives Part of the Complex Bone Phenotype in Mice Deficient for Memo1. Matthias B Moor,1 Suresh K Ramakrishnan,1 Finola L. (2018). JBMR1 Plus, Vol. xx,

Renal Memo1 Differentially Regulates the Expression of Vitamin D-Dependent Distal Renal Tubular Calcium Transporters. Moor, Matthias B; Haenzi, Barbara; Legrand, Finola; Koesters, Robert; Hynes, Nancy E; Bonny, Olivier. (2018). Frontiers in physiology 9: 874

Serum calcification propensity is independently associated with disease activity in systemic lupus erythematosus. Dahdal, Suzan; Devetzis, Vasilios; Chalikias, George; Tziakas, Dimitrios; Chizzolini, Carlo; Ribi, Camillo; Trendelenburg, Marten; Eisenberger, Ute; Hauser, Thomas; Pasch, Andreas; Huynh-Do, Uyen; Arampatzis, Spyridon; . (2018). PloS one 13(1): 0188695

Source and microenvironmental regulation of erythropoietin in the kidney. Nolan, Karen A; Wenger, Roland H. (2018). Current opinion in nephrology and hypertension 27(4): 277-282

The excretion of uromodulin is modulated by the calcium-sensing receptor. Tokonami, Natsuko; Olinger, Eric; Debaix, Huguette; Houillier, Pascal; Devuyst, Olivier. (2018). Kidney international 94(5): 882-886

The targeted anti-oxidant MitoQ causes mitochondrial swelling and depolarization in kidney tissue. Gottwald, Esther M.; Duss, Michael; Bugarski, Milica; Haenni, Dominik; Schuh, Claus D.; Landau, Ehud M.; Hall, Andrew M.. (2018). Physiological reports 6(7): 13667

Uromodulin and Nephron Mass. Pivin, Edward; Ponte, Belen; de Seigneux, Sophie; Ackermann, Daniel; Guessous, Idris; Ehret, Georg; Pechère-Bertschi, Antoinette; Olinger, Eric; Mohaupt, Markus; Vogt, Bruno; Martin, Pierre-Yves; Burnier, Michel; Bochud, Murielle; Devuyst, Olivier; Pruijm, Menno. (2018). Clinical journal of the American Society of Nephrology : CJASN 13(10): 1556-1557

Uromodulin is expressed in the distal convoluted tubule, where it is critical for regulation of the sodium chloride cotransporter NCC. Tokonami, Natsuko; Takata, Tomoaki; Beyeler, Jan; Ehrbar, Iris; Yoshifuji, Ayumi; Christensen, Erik I; Loffing, Johannes; Devuyst, Olivier; Olinger, Eric G. (2018). Kidney international 94(4): 701-715

Virtual surgical planning, flow simulation and 3D electro-spinning of patient-specific grafts to optimize Fontan hemodynamics. Siallagan, Dominik; Loke, Yue-Hin; Olivieri, Laura; Opfermann, Justin; Ong, Chin Siang; de Zélicourt, Diane; Petrou, Anastasios; Daners, Marianne Schmid; Kurtcuoglu, Vartan; Meboldt, Mirko; Nelson, Kevin; Vricella, Luca; Johnson, Jed; Hibino, Narutoshi; Krieger, Axel. (2018). The Journal of Thoracic and Cardiovascular Surgery 155(4): 1734-1742

Renal dysfunction induced by kidney-specific gene deletion of Hsd11b2 as a primary cause of salt-dependent hypertension. Ueda, Kohei; Nishimoto, Mitsuhiro; Hirohama, Daigoro; Ayuzawa, Nobuhiro; Kawarazaki, Wakako; Watanabe, Atsushi; Shimosawa, Tatsuo; Loffing, Johannes; Zhang, Ming-Zhi; Marumo, Takeshi; Fujita, Toshiro. (2017). Hypertension (Dallas, Tex. : 1979) 70(1): 111-118

A population-based approach to assess the heritability and distribution of renal handling of electrolytes. Moulin, Flore; Ponte, Belen; Pruijm, Menno; Ackermann, Daniel; Bouatou, Yassine; Guessous, Idris; Ehret, Georg; Bonny, Olivier; Pechère-Bertschi, Antoinette; Staessen, Jan A.; Paccaud, Fred; Martin, Pierre-Yves; Burnier, Michel; Vogt, Bruno; Devuyst, Olivier; Bochud, Murielle. (2017). Kidney international 92(6): 1536-1543

Acute Adaption to Oral or Intravenous Phosphate Requires Parathyroid Hormone. Thomas, Linto; Bettoni, Carla; Knöpfel, Thomas; Hernando, Nati; Biber, Jürg; Wagner, Carsten A.. (2017). Journal of the American Society of Nephrology : JASN 28(3): 903-914

Adventitia and perivascular adipose tissue - the integral unit in vascular disease. Zhihong Yang and Xiu-Fen Ming. (2017). European Textbook of Vascular Biology, OXFORD University Press, 2017: pp 309-320

And the fat lady sings about phosphate and calcium. Wagner, Carsten A.; Imenez Silva, Pedro H.; Rubio-Aliaga, Isabel. (2017). Kidney international 91(2): 270-272

Antagonism of profibrotic microRNA-21 improves outcome of murine chronic renal allograft dysfunction. Schauerte, Celina; Hübner, Anika; Rong, Song; Wang, Shijun; Shushakova, Nelli; Mengel, Michael; Dettling, Angela; Bang, Claudia; Scherf, Kristian; Koelling, Malte; Melk, Anette; Haller, Hermann; Thum, Thomas; Lorenzen, Johan M.. (2017). Kidney international 92(3): 646-656

Arginase-I enhances vascular endothelial inflammation and senescence through eNOS-uncoupling. Zhu, Cuicui; Yu, Yi; Montani, Jean-Pierre; Ming, Xiu-Fen; Yang, Zhihong. (2017). BMC research notes 10(1): 82

Arginase-II Deficiency Extends Lifespan in Mice. Xiong, Yuyan; Yepuri, Gautham; Montani, Jean-Pierre; Ming, Xiu-Fen; Yang, Zhihong. (2017). Frontiers in physiology 8: 682

Arginase-II Promotes Tumor Necrosis Factor-α Release From Pancreatic Acinar Cells Causing β-Cell Apoptosis in Aging. Xiong, Yuyan; Yepuri, Gautham; Necetin, Sevil; Montani, Jean-Pierre; Ming, Xiu-Fen; Yang, Zhihong. (2017). Diabetes 66(6): 1636-1649

Autosomal dominant polycystic kidney disease: Novel management and treatment concepts. Lorenzen JM, Wüthrich RP. (2017). Der Nephrologe; 2017, 297-309

Blood pump design variations and their influence on hydraulic performance and indicators of hemocompatibility. L. Wiegmann, S. Boës, D. de Zélicourt,; B. Thamsen, M. Schmid Daners,; M. Meboldt, V. Kurtcuoglu,. (2017). Annals of Biomedical Engineering

Changes in urinary risk profile after short-term low sodium and low calcium diet in recurrent Swiss kidney stone formers. Seeger, Harald; Kaelin, Andrea; Ferraro, Pietro M.; Weber, Damian; Jaeger, Philippe; Ambuehl, Patrice; Robertson, William G.; Unwin, Robert; Wagner, Carsten A.; Mohebbi, Nilufar. (2017). BMC nephrology 18(1): 349

Common variants in CLDN14 are associated with differential excretion of magnesium over calcium in urine. Corre, Tanguy; Olinger, Eric; Harris, Sarah E.; Traglia, Michela; Ulivi, Sheila; Lenarduzzi, Stefania; Belge, Hendrica; Youhanna, Sonia; Tokonami, Natsuko; Bonny, Olivier; Houillier, Pascal; Polasek, Ozren; Deary, Ian J.; Starr, John M.; Toniolo, Daniela; Gasparini, Paolo; Vollenweider, Peter; Hayward, Caroline; Bochud, Murielle; Devuyst, Olivier. (2017). Pflugers Archiv : European journal of physiology 469(1): 91-103

Comparative transcriptomic analysis identifies evolutionarily conserved gene products in the vertebrate renal distal convoluted tubule. Sugano, Yuya; Cianciolo Cosentino, Chiara; Loffing-Cueni, Dominique; Neuhauss, Stephan C. F.; Loffing, Johannes. (2017). Pflugers Archiv : European journal of physiology 469(7-8): 859-867

Comparison of anti-siphon devices—how do they affect CSF dynamics in supine and upright posture?. Gehlen, Manuel; Eklund, Anders; Kurtcuoglu, Vartan; Malm, Jan; Schmid Daners, Marianne. (2017). Acta Neurochirurgica

Comparison of readout-segmented and conventional single-shot for echo-planar diffusion-weighted imaging in the assessment of kidney interstitial fibrosis. Friedli, Iris; Crowe, Lindsey Alexandra; de Perrot, Thomas; Berchtold, Lena; Martin, Pierre-Yves; de Seigneux, Sophie; Vallée, Jean-Paul. (2017). Journal of magnetic resonance imaging : JMRI

Coupling between phosphate and calcium homeostasis: a mathematical model. Granjon, David; Bonny, Olivier; Edwards, Aurélie. (2017). American journal of physiology. Renal physiology 313(6): 1181-1199

Dietary sodium induces a redistribution of the tubular metabolic workload. Udwan, Khalil; Abed, Ahmed; Roth, Isabelle; Dizin, Eva; Maillard, Marc; Bettoni, Carla; Loffing, Johannes; Wagner, Carsten A.; Edwards, Aurélie; Feraille, Eric. (2017). The Journal of physiology 595(22): 6905-6922

Endothelin-1 mediates natriuresis but not polyuria during vitamin D-induced acute hypercalcemia. Tokonami, Natsuko; Cheval, Lydie; Monnay, Isabelle; Meurice, Guillaume; Loffing, Johannes; Feraille, Eric; Houillier, Pascal. (2017). The Journal of physiology 595(8): 2535-2550

Expression and regulation of the neutral amino acid transporter B0AT1 in rat small intestine. Jando, Julia; Camargo, Simone M. R.; Herzog, Brigitte; Verrey, François. (2017). PloS one 12(9): 0184845

Hydrogen sulfide attenuates calcification of vascular smooth muscle cells via KEAP1/NRF2/NQO1 activation. Aghagolzadeh, Parisa; Radpour, Ramin; Bachtler, Matthias; van Goor, Harry; Smith, Edward R.; Lister, Adam; Odermatt, Alex; Feelisch, Martin; Pasch, Andreas. (2017). Atherosclerosis 265: 78-86

Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation. Cosin-Roger, Jesus; Simmen, Simona; Melhem, Hassan; Atrott, Kirstin; Frey-Wagner, Isabelle; Hausmann, Martin; de Vallière, Cheryl; Spalinger, Marianne R.; Spielmann, Patrick; Wenger, Roland H.; Zeitz, Jonas; Vavricka, Stephan R.; Rogler, Gerhard; Ruiz, Pedro A.. (2017). Nature communications 8(1): 98

Increased bone resorption by osteoclast-specific deletion of the sodium/calcium exchanger isoform 1 (NCX1). Albano, Giuseppe; Dolder, Silvia; Siegrist, Mark; Mercier-Zuber, Annie; Auberson, Muriel; Stoudmann, Candice; Hofstetter, Willy; Bonny, Olivier; Fuster, Daniel G.. (2017). Pflugers Archiv : European journal of physiology 469(2): 225-233

Influence of Standard Laboratory Procedures on Measures of Erythrocyte Damage. Wiegmann, Lena; de Zélicourt, Diane A.; Speer, Oliver; Muller, Alissa; Goede, Jeroen S.; Seifert, Burkhardt; Kurtcuoglu, Vartan. (2017). Frontiers in physiology 8: 731

Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells. Alesutan, Ioana; Voelkl, Jakob; Feger, Martina; Kratschmar, Denise V.; Castor, Tatsiana; Mia, Sobuj; Sacherer, Michael; Viereck, Robert; Borst, Oliver; Leibrock, Christina; Gawaz, Meinrad; Kuro-o, Makoto; Pilz, Stefan; Tomaschitz, Andreas; Odermatt, Alex; Pieske, Burkert; Wagner, Carsten A.; Lang, Florian. (2017). Scientific reports 7(1): 2059

Is posture-related craniospinal compliance shift caused by jugular vein collapse? A theoretical analysis. Gehlen, Manuel; Kurtcuoglu, Vartan; Schmid Daners, Marianne. (2017). Fluids and Barriers of the CNS 14(1): 5

Long noncoding RNAs - Molecular switch and therapeutic target molecules of disease processes. Lorenzen, Johan M.; Thum, Thomas. (2017). Der Nephrologe; 2017, Volume 12, Issue 1, pp 59–62

Nephrotic Syndrome in Small Cell Lung Cancer and Induction of C-Mip in Podocytes. Bouatou, Yassine; Koessler, Thibaud; Oniszczuk, Julie; Zhang, Shao-Yu; Moll, Solange; Audard, Vincent; de Seigneux, Sophie; Sahali, Djillali. (2017). American journal of kidney diseases : the official journal of the National Kidney Foundation 69(3): 477-480

New frontiers in intravital microscopy of the kidney. Hall, Andrew M.; Schuh, Claus D.; Haenni, Dominik. (2017). Current opinion in nephrology and hypertension 26(3): 172-178

On the relationship between proteinuria and plasma phosphate. de Seigneux, Sophie; Wilhelm-Bals, Alexandrab; Courbebaisse, Mariec. (2017). Swiss medical weekly 147: 14509

Pathophysiology, diagnosis and treatment of inherited distal renal tubular acidosis. Mohebbi, Nilufar; Wagner, Carsten A.. (2017). Journal of nephrology

Podocytes regulate the glomerular basement membrane protein nephronectin by means of miR-378a-3p in glomerular diseases. Müller-Deile, Janina; Dannenberg, Jan; Schroder, Patricia; Lin, Meei-Hua; Miner, Jeffrey H.; Chen, Rongjun; Bräsen, Jan-Hinrich; Thum, Thomas; Nyström, Jenny; Staggs, Lynne Beverly; Haller, Hermann; Fiedler, Jan; Lorenzen, Johan M.; Schiffer, Mario. (2017). Kidney international 92(4): 836-849

Preventing the Progression of AKI to CKD: The Role of Mitochondria. de Seigneux, Sophie; Martin, Pierre-Yves. (2017). Journal of the American Society of Nephrology : JASN

Primary cilia control the maturation of tubular lumen in renal collecting duct epithelium. Ernandez, Thomas; Komarynets, Olga; Chassot, Alexandra; Sougoumarin, Soushma; Soulié, Priscilla; Wang, Yubao; Montesano, Roberto; Feraille, Eric. (2017). American journal of physiology. Cell physiology 313(1): 94-107

Protein Phosphatase 1α enhances renal aldosterone signaling via mineralocorticoid receptor stabilization. Nagarajan, Shunmugam; Vohra, Twinkle; Loffing, Johannes; Faresse, Nourdine. (2017). Molecular and cellular endocrinology 450: 74-82

Protocol for a prospective, controlled, observational study to evaluate the influence of hypoxia on healthy volunteers and patients with inflammatory bowel disease: the Altitude IBD Study. Vavricka, Stephan; Ruiz, Pedro A; Scharl, Sylvie; Biedermann, Luc; Scharl, Michael; de Vallière, Cheryl; Lundby, Carsten; Wenger, Roland H; Held, Leonhard; Merz, Tobias M; Gassmann, Max; Lutz, Thomas; Kunz, Andres; Bron, Denis; Fontana, Adriano; Strauss, Laura; Weber, Achim; Fried, Michael; Rogler, Gerhard; Zeitz, Jonas. (2017). BMJ open 7(1): 013477

Quantifying the relative contributions of different solute carriers to aggregate substrate transport. Taslimifar, Mehdi; Oparija, Lalita; Verrey, Francois; Kurtcuoglu, Vartan; Olgac, Ufuk; Makrides, Victoria. (2017). Scientific reports 7: 40628

Rapid adaptation to microgravity in mammalian macrophage cells. Thiel, Cora S.; de Zélicourt, Diane; Tauber, Svantje; Adrian, Astrid; Franz, Markus; Simmet, Dana M.; Schoppmann, Kathrin; Hauschild, Swantje; Krammer, Sonja; Christen, Miriam; Bradacs, Gesine; Paulsen, Katrin; Wolf, Susanne A.; Braun, Markus; Hatton, Jason; Kurtcuoglu, Vartan; Franke, Stefanie; Tanner, Samuel; Cristoforetti, Samantha; Sick, Beate; Hock, Bertold; Ullrich, Oliver. (2017). Scientific reports 7(1): 43

Reduced β-catenin expression affects patterning of bone primordia, but not bone maturation. Pflug, Tobias; Huynh-Do, Uyen; Rudloff, Stefan. (2017). Biology open 6(5): 582-588

Renal arteriovenous oxygen shunting. Kuo, Willy; Kurtcuoglu, Vartan. (2017). Current opinion in nephrology and hypertension 26(4): 290-295

Renal Fanconi Syndrome and Hypophosphatemic Rickets in the Absence of Xenotropic and Polytropic Retroviral Receptor in the Nephron. Ansermet, Camille; Moor, Matthias B.; Centeno, Gabriel; Auberson, Muriel; Hu, Dorothy Zhang; Baron, Roland; Nikolaeva, Svetlana; Haenzi, Barbara; Katanaeva, Natalya; Gautschi, Ivan; Katanaev, Vladimir; Rotman, Samuel; Koesters, Robert; Schild, Laurent; Pradervand, Sylvain; Bonny, Olivier; Firsov, Dmitri. (2017). Journal of the American Society of Nephrology : JASN 28(4): 1073-1078

Renal phosphate handling and inherited disorders of phosphate reabsorption: an update. Wagner, Carsten A.; Rubio-Aliaga, Isabel; Hernando, Nati. (2017). Pediatric nephrology (Berlin, Germany)

Renal Tubular Ubiquitin-Protein Ligase NEDD4-2 Is Required for Renal Adaptation during Long-Term Potassium Depletion. Al-Qusairi, Lama; Basquin, Denis; Roy, Ankita; Rajaram, Renuga Devi; Maillard, Marc P.; Subramanya, Arohan R.; Staub, Olivier. (2017). Journal of the American Society of Nephrology : JASN

Selective Deletion of Sodium Salt Taste during Development Leads to Expanded Terminal Fields of Gustatory Nerves in the Adult Mouse Nucleus of the Solitary Tract. Sun C, Hummler E, Hill DL.. (2017). J Neurosci 37(3): 660-672

Severe hyperkalemia is rescued by low-potassium diet in renal βENaC-deficient mice. Boscardin, Emilie; Perrier, Romain; Sergi, Chloé; Maillard, Marc; Loffing, Johannes; Loffing-Cueni, Dominique; Koesters, Robert; Rossier, Bernard Claude; Hummler, Edith. (2017). Pflugers Archiv : European journal of physiology 469(10): 1387-1399

The breakup of intravascular microbubbles and its impact on the endothelium. Wiedemair, Wolfgang; Tukovic, Zeljko; Jasak, Hrvoje; Poulikakos, Dimos; Kurtcuoglu, Vartan. (2017). Biomechanics and modeling in mechanobiology 16(2): 611-624

The functional interplay between the HIF pathway and the ubiquitin system - more than a one-way road. Günter, Julia; Ruiz-Serrano, Amalia; Pickel, Christina; Wenger, Roland H.; Scholz, Carsten C.. (2017). Experimental cell research

The Hypertension Pandemic: An Evolutionary Perspective. Rossier, Bernard C.; Bochud, Murielle; Devuyst, Olivier. (2017). Physiology (Bethesda, Md.) 32(2): 112-125

The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction. Knöpfel, Thomas; Pastor-Arroyo, Eva M.; Schnitzbauer, Udo; Kratschmar, Denise V.; Odermatt, Alex; Pellegrini, Giovanni; Hernando, Nati; Wagner, Carsten A.. (2017). Scientific reports 7(1): 11018

The Swiss Kidney Stone Cohort: An Observational Study to Unravel the Cause of Renal Stone Formation. Roth, Beat; Bonny, Olivier. (2017). European urology focus 3(1): 7-9

Ticagrelor, but not clopidogrel, reduces arterial thrombosis via endothelial tissue factor suppression. Reiner, Martin F.; Akhmedov, Alexander; Stivala, Simona; Keller, Stephan; Gaul, Daniel S.; Bonetti, Nicole R.; Savarese, Gianluigi; Glanzmann, Martina; Zhu, Cuicui; Ruf, Wolfram; Yang, Zhihong; Matter, Christian M.; Lüscher, Thomas F.; Camici, Giovanni G.; Beer, Juerg H.. (2017). Cardiovascular research 113(1): 61-69

Uninephrectomy and apical fluid shear stress decrease ENaC abundance in collecting duct principal cells. Ernandez, T.; Udwan, K.; Chassot, A.; Martin, P.-Y.; Feraille, E.. (2017). American journal of physiology. Renal physiology: 002002017-002002017

Uromodulin: from physiology to rare and complex kidney disorders. Devuyst, Olivier; Olinger, Eric; Rampoldi, Luca. (2017). Nature reviews. Nephrology 13(9): 525-544

Genetic kidney diseases: new perspectives on diagnosis. Paoloni-Giacobino, Ariane; De Seigneux, Sophie; Parvex, Paloma; Bouatou, Yassine. (2016). Revue medicale suisse 12(507)

A model of calcium homeostasis in the rat. Granjon, David; Bonny, Olivier; Edwards, Aurélie. (2016). American journal of physiology. Renal physiology 311(5): 1047-1062

Adaptation of Opossum Kidney Cells to Luminal Phosphate: Effects of Phosphonoformic Acid and Kinase Inhibitors. Thomas, Linto; Wagner, Carsten A.; Biber, Jürg; Hernando, Nati. (2016). Kidney & blood pressure research 41(3): 298-310

Adipocyte glucocorticoid receptor has a minor contribution in adipose tissue growth. Desarzens, Sébastien; Faresse, Nourdine. (2016). Journal of Endocrinology 230(1): 1-11

Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype. Canonica, Jérémie; Sergi, Chloé; Maillard, Marc; Klusonova, Petra; Odermatt, Alex; Koesters, Robert; Loffing-Cueni, Dominique; Loffing, Johannes; Rossier, Bernard; Frateschi, Simona; and Hummler, Edith. (2016). Pflugers Arch 468(5): 895-908

Altered Prostasin (CAP1/Prss8) Expression Favors Inflammation and Tissue Remodeling in DSS-induced Colitis. Anna Keppner, PhD Sumedha Malsure, PhD Antoine Nob; Olivier Bonny, MD, PhD Edith Hummler, PhD. (2016). Inflamm Bowel Dis 22(12): 2824-2839

Associations of Urinary Uromodulin with Clinical Characteristics and Markers of Tubular Function in the General Population. Pruijm, Menno; Ponte, Belen; Ackermann, Daniel; Paccaud, Fred; Guessous, Idris; Ehret, Georg; Pechère-Bertschi, Antoinette; Vogt, Bruno; Mohaupt, Markus G.; Martin, Pierre-Yves; Youhanna, Sonia C.; Nägele, Nadine; Vollenweider, Peter; Waeber, Gérard; Burnier, Michel; Devuyst, Olivier; Bochud, Murielle. (2016). Clinical Journal of the American Society of Nephrology 11(1): 70-80

Autosomal-Recessive Mutations in SLC34A1 Encoding Sodium-Phosphate Cotransporter 2A Cause Idiopathic Infantile Hypercalcemia. Schlingmann, K. P.; Ruminska, J.; Kaufmann, M.; Dursun, I.; Patti, M.; Kranz, B.; Pronicka, E.; Ciara, E.; Akcay, T.; Bulus, D.; Cornelissen, E. A. M.; Gawlik, A.; Sikora, P.; Patzer, L.; Galiano, M.; Boyadzhiev, V.; Dumic, M.; Vivante, A.; Kleta, R.; Dekel, B.; Levtchenko, E.; Bindels, R. J.; Rust, S.; Forster, I. C.; Hernando, N.; Jones, G.; Wagner, C. A.; Konrad, M.. (2016). Journal of the American Society of Nephrology 27(2): 604-614

Bidirectional signalling between EphA2 and ephrinA1 increases tubular cell attachment, laminin secretion and modulates erythropoietin expression after renal hypoxic injury. Rodriguez, Stéphane; Rudloff, Stefan; Koenig, Katrin Franziska; Karthik, Swapna; Hoogewijs, David; Huynh-Do, Uyen. (2016). Pflugers Archiv : European journal of physiology 468(8): 1433-48

Brain interstitial fluid glutamine homeostasis is controlled by blood–brain barrier SLC7A5/LAT1 amino acid transporter. Dolgodilina, Elena; Imobersteg, Stefan; Laczko, Endre; Welt, Tobias; Verrey, Francois; Makrides, Victoria. (2016). Journal of Cerebral Blood Flow & Metabolism 36(11): 1929-1941

Calcification of vascular smooth muscle cells is induced by secondary calciprotein particles and enhanced by tumor necrosis factor-α. Aghagolzadeh, Parisa; Bachtler, Matthias; Bijarnia, Rakesh; Jackson, Christopher; Smith, Edward R.; Odermatt, Alex; Radpour, Ramin; Pasch, Andreas. (2016). Atherosclerosis 251: 404-14

Clinical, Genetic, and Urinary Factors Associated with Uromodulin Excretion. Troyanov, Stéphan; Delmas-Frenette, Catherine; Bollée, Guillaume; Youhanna, Sonia; Bruat, Vanessa; Awadalla, Philip; Devuyst, Olivier; Madore, François. (2016). Clinical Journal of the American Society of Nephrology 11(1): 62-69

Colocalization of the (Pro)renin Receptor/Atp6ap2 with H+-ATPases in Mouse Kidney but Prorenin Does Not Acutely Regulate Intercalated Cell H+-ATPase Activity. Daryadel, Arezoo; Bourgeois, Soline; Figueiredo, Marta F. L.; Gomes Moreira, Ana; Kampik, Nicole B.; Oberli, Lisa; Mohebbi, Nilufar; Lu, Xifeng; Meima, Marcel E.; Danser, A. H. Jan; Wagner, Carsten A.. (2016). PLOS ONE 11(1): e0147831

Coordinated Control of ENaC and Na+,K+-ATPase in Renal Collecting Duct. Feraille, E.; Dizin, E.. (2016). Journal of the American Society of Nephrology : JASN 27(9): 2554-63

Development and characterization of a pseudo multiple reaction monitoring method for the quantification of human uromodulin in urine. Hammond, T. G. Moes, S. Youhanna, S. Jennings, P.. (2016). Bioanalysis 8(12): 1279-96

Did you know? Neocytolysis, how to halt EPO. Persson, Pontus B.; Wenger, Roland H.; Lundby, Carsten; Gunga, Hanns-Christian. (2016). Acta Physiologica: n/a-n/a

Effects of potassium citrate or potassium chloride in patients with combined glucose intolerance: A placebo-controlled pilot study. Conen, Katrin; Scanni, Roberto; Gombert, Marie-Therese; Hulter, Henry N.; Krapf, Reto. (2016). Journal of diabetes and its complications 30(6): 1158-61

En Face Detection of Nitric Oxide and Superoxide in Endothelial Layer of Intact Arteries. Yu Y, Xiong Y, Montani JP, Yang Z, Ming XF.. (2016). J Vis Exp(108): 53718

Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2α in invasive breast cancer cells. Fuady, Jerry H.; Gutsche, Katrin; Santambrogio, Sara; Varga, Zsuzsanna; Hoogewijs, David; Wenger, Roland H.. (2016). Oncotarget 7(21): 31153-65

Extracellular K(+) rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl(-) -dependent and independent mechanisms. Penton, David; Czogalla, Jan; Wengi, Agnieszka; Himmerkus, Nina; Loffing-Cueni, Dominique; Carrel, Monique; Rajaram, Renuga Devi; Staub, Olivier; Bleich, Markus; Schweda, Frank; Loffing, Johannes. (2016). The Journal of physiology 594(21): 6319-6331

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1. Scholz, Carsten C.; Rodriguez, Javier; Pickel, Christina; Burr, Stephen; Fabrizio, Jacqueline-alba; Nolan, Karen A.; Spielmann, Patrick; Cavadas, Miguel A. S.; Crifo, Bianca; Halligan, Doug N.; Nathan, James A.; Peet, Daniel J.; Wenger, Roland H.; Von Kriegsheim, Alex; Cummins, Eoin P.; Taylor, Cormac T.. (2016). PLOS Biology 14(1): e1002347

Formation of Renal Cysts and Tumors in Vhl/Trp53-Deficient Mice Requires HIF1α and HIF2α. Schönenberger, Désirée; Harlander, Sabine; Rajski, Michal; Jacobs, Robert A.; Lundby, Anne-Kristine; Adlesic, Mojca; Hejhal, Tomas; Wild, Peter J.; Lundby, Carsten; Frew, Ian J.. (2016). Cancer Research 76(7): 2025-2036

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Pattaro, Cristian; Teumer, Alexander; Gorski, Mathias; et al.. (2016). Nature communications 7: 10023

Genetic Targeting of Arginase-II in Mouse Prevents Renal Oxidative Stress and Inflammation in Diet-Induced Obesity. Huang, Ji; Rajapakse, Angana; Xiong, Yuyan; Montani, Jean-Pierre; Verrey, François; Ming, Xiu-Fen; Yang, Zhihong. (2016). Frontiers in physiology 7: 560

Glymphatic solute transport does not require bulk flow. Asgari, Mahdi; de Zélicourt, Diane; Kurtcuoglu, Vartan. (2016). Scientific reports 6: 38635

In vivo characterization of the integration and vascularization of a silk-derived surgical scaffold. Kijanska, Monika; Marmaras, Anastasios; Hegglin, Alicia; Kurtcuoglu, Vartan; Giovanoli, Pietro; Lindenblatt, Nicole. (2016). Journal of Plastic, Reconstructive & Aesthetic Surgery 69(8): 1141-1150

Increased Synthesis of Liver Erythropoietin with CKD. de Seigneux, S.; Lundby, A.-K. M.; Berchtold, L.; Berg, A. H.; Saudan, P.; Lundby, C.. (2016). Journal of the American Society of Nephrology : JASN 27(8): 2265-2269

Long wavelength multiphoton excitation is advantageous for intravital kidney imaging. Schuh, C.D.; Haenni, D.; Craigie, E.; Ziegler, U.; Weber, B.; Devuyst, O.; Hall, Andrew M.. (2016). Kidney international 89(3): 712-719

Loss of function mutation of the Slc38a3 glutamine transporter reveals its critical role for amino acid metabolism in the liver, brain, and kidney. Chan, Kessara; Busque, Stephanie M.; Sailer, Manuela; Stoeger, Claudia; Bröer, Stefan; Daniel, Hannelore; Rubio-Aliaga, Isabel; Wagner, Carsten A.. (2016). Pflügers Archiv - European Journal of Physiology 468(2): 213-227

Mitochondria as therapeutic targets in acute kidney injury. Hall, Andrew M.; Schuh, Claus D.. (2016). Current opinion in nephrology and hypertension 25(4): 355-62

NADPH oxidase 4 deficiency increases tubular cell death during acute ischemic reperfusion injury. Nlandu-Khodo, Stellor; Dissard, Romain; Hasler, Udo; Schäfer, Matthias; Pircher, Haymo; Jansen-Durr, Pidder; Krause, Karl Heinz; Martin, Pierre-Yves; de Seigneux, Sophie. (2016). Scientific reports 6: 38598

New Magnetic Resonance Imaging Index for Renal Fibrosis Assessment: A Comparison between Diffusion-Weighted Imaging and T1 Mapping with Histological Validation. Friedli, I.; Crowe, L. A.; Berchtold, L.; Moll, S.; Hadaya, K.; de Perrot, T.; Vesin, C.; Martin, P.-Y.; de Seigneux, S.; Vallée, J.-P.. (2016). Scientific reports 6: 30088

NFκB-sensitive Orai1 expression in the regulation of FGF23 release. Zhang, Bingbing; Yan, Jing; Umbach, Anja T.; Fakhri, Hajar; Fajol, Abul; Schmidt, Sebastian; Salker, Madhuri S.; Chen, Hong; Alexander, Dorothea; Spichtig, Daniela; Daryadel, Arezoo; Wagner, Carsten A.; Föller, Michael; Lang, Florian. (2016). Journal of Molecular Medicine 94(5): 557-566

Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice. Mulay, Shrikant R.; Eberhard, Jonathan N.; Pfann, Victoria; Marschner, Julian A.; Darisipudi, Murthy N.; Daniel, Christoph; Romoli, Simone; Desai, Jyaysi; Grigorescu, Melissa; Kumar, Santhosh V.; Rathkolb, Birgit; Wolf, Eckhard; Hrabě de Angelis, Martin; Bäuerle, Tobias; Dietel, Barbara; Wagner, Carsten A.; Amann, Kerstin; Eckardt, Kai-Uwe; Aronson, Peter S.; Anders, Hans Joachim; Knauf, Felix. (2016). American Journal of Physiology - Renal Physiology

Oxygen-dependent regulation of aquaporin-3 expression. Hoogewijs, D; Vogler, Melanie; Zwenger, Eveline; Krull, Sabine; Zieseniss, Anke. (2016). Hypoxia (Auckl): 91-97

Patient Specific Hardware-in-the-Loop Testing of Cerebrospinal Fluid Shunt Systems. Gehlen, Manuel; Kurtcuoglu, Vartan; Daners, Marianne Schmid. (2016). IEEE Transactions on Biomedical Engineering 63(2): 348-358

Patient-Specific Surgical Planning, Where Do We Stand? The Example of the Fontan Procedure. de Zélicourt, Diane A.; Kurtcuoglu, Vartan. (2016). Annals of Biomedical Engineering 44(1): 174-186

Pendrin-A New Target for Diuretic Therapy?. Wagner, C. A.. (2016). Journal of the American Society of Nephrology : JASN 27(12): 3499-3501

Phosphate and FGF23 in the renoprotective benefit of RAAS inhibition. de Seigneux, Sophie; Martin, Pierre-Yves. (2016). Pharmacological research 106: 87-91

Phosphocalcic Markers and Calcification Propensity for Assessment of Interstitial Fibrosis and Vascular Lesions in Kidney Allograft Recipients. Berchtold, Lena; Ponte, Belen; Moll, Solange; Hadaya, Karine; Seyde, Olivia; Bachtler, Matthias; Vallée, Jean-Paul; Martin, Pierre-Yves; Pasch, Andreas; de Seigneux, Sophie. (2016). PloS one 11(12): 0167929-0167929

Polymorphisms in the lectin pathway of complement activation influence the incidence of acute rejection and graft outcome after kidney transplantation. Golshayan, Déla; Wójtowicz, Agnieszka; Bibert, Stéphanie; et. al. (2016). Kidney International 89(4): 927-938

Potassium depletion stimulates Na-Cl cotransporter via phosphorylation and inactivation of the ubiquitin ligase Kelch-like 3. Ishizawa, Kenichi; Xu, Ning; Loffing, Johannes; Lifton, Richard P; Fujita, Toshiro; Uchida, Shunya; Shibata, Shigeru. (2016). Biochem Biophys Res Commun 480(4): 745-751

Real-time functional characterization of cationic amino acid transporters using a new FRET sensor. Vanoaica, Liviu; Behera, Alok; Camargo, Simone M. R.; Forster, Ian C.; Verrey, François. (2016). Pflugers Archiv : European journal of physiology 468(4): 563-572

Reducing αENaC expression in the kidney connecting tubule induces pseudohypoaldosteronism type 1 symptoms during K+ loading. Poulsen, Søren Brandt; Praetorius, Jeppe; Damkier, Helle H.; Miller, Lance; Nelson, Raoul D.; Hummler, Edith; Christensen, Birgitte Mønster. (2016). American Journal of Physiology - Renal Physiology 310(4): F300-F310

Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC. Al-Qusairi, Lama; Basquin, Denis; Roy, Ankita; Stifanelli, Matteo; Rajaram, Renuga Devi; Debonneville, Anne; Nita, Izabela; Maillard, Marc; Loffing, Johannes; Subramanya, Arohan R.; Staub, Olivier. (2016). American journal of physiology. Renal physiology 311(2): 330-342

Severe Salt-Losing Syndrome and Hyperkalemia Induced by Adult Nephron-Specific Knockout of the Epithelial Sodium Channel -Subunit. Perrier, R.; Boscardin, E.; Malsure, S.; Sergi, C.; Maillard, M. P.; Loffing, J.; Loffing-Cueni, D.; Sorensen, M. V.; Koesters, R.; Rossier, B. C.; Frateschi, S.; Hummler, E.. (2016). Journal of the American Society of Nephrology 27(8): 2309-2318

Targeting arginase-II protects mice from high-fat-diet-induced hepatic steatosis through suppression of macrophage inflammation. Liu C, Rajapakse AG, Riedo E, Fellay B; Bernhard M, Montani J, Yang Z, Ming XF. (2016). Sci Rep 6: 20405

The Bohr Effect Is Not a Likely Promoter of Renal Preglomerular Oxygen Shunting. Olgac, Ufuk; Kurtcuoglu, Vartan. (2016). Frontiers in physiology 7: 482-482

The DESCARTES-Nantes survey of kidney transplant recipients displaying clinical operational tolerance identifies 35 new tolerant patients and 34 almost tolerant patients. Massart, Annick; Pallier, Annaïck; Pascual, Julio, et al. (2016). Nephrology Dialysis Transplantation 31(6): 1002-1013

The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na(+) channel (ENaC): IUPHAR Review 19. Boscardin E, Alijevic O, Hummler E, Frateschi S; Kellenberger S.. (2016). Br J Pharmacol 173(18): 2671-2701

The mineralocorticoid receptor (MR) regulates ENaC but not NCC in mice with random MR deletion. Czogalla, J.; Vohra, T.; Penton, D.; Kirschmann, M.; Craigie, E.; Loffing J.. (2016). Pflugers Arch 468(5)

The Mouse Isolated Perfused Kidney Technique. Czogalla, J; Schweda, F.; Loffing, J.. (2016). J Vis Exp: 117

The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases. Kühn, Nora; Bergmann, Silke; Kösterke, Nadine; Lambertz, Ruth L. O.; Keppner, Anna; van den Brand, Judith M. A.; Pöhlmann, Stefan; Weiß, Siegfried; Hummler, Edith; Hatesuer, Bastian; Schughart, Klaus. (2016). Journal of Virology 90(9): 4298-4307

The Three "Musketairs" - Lasker Prize 2016 goes to the protagonists of hypoxia research. Wenger, Roland; Katschinski, Doerthe. (2016). Hypoxia (Auckland, N.Z.) 4: 161-162

The Uromodulin Gene Locus Shows Evidence of Pathogen Adaptation through Human Evolution. Ghirotto, S.; Tassi, F.; Barbujani, G.; Pattini, L.; Hayward, C.; Vollenweider, P.; Bochud, M.; Rampoldi, L.; Devuyst, O.. (2016). Journal of the American Society of Nephrology : JASN 27(10): 2983-2996

TRPV4 is associated with central rather than nephrogenic osmoregulation. Sylvie JanasFrançois SeghersOlivier Schakman; Mohammad AlsadyPeter DeenJoris Vriens; Fadel TissirBernd NiliusJohannes LoffingPhilippe. (2016). Pflugers Arch 468(9)

Up-regulation of FGF23 release by aldosterone. Zhang, Bingbing; Umbach, Anja T.; Chen, Hong; Yan, Jing; Fakhri, Hajar; Fajol, Abul; Salker, Madhuri S.; Spichtig, Daniela; Daryadel, Arezoo; Wagner, Carsten A.; Föller, Michael; Lang, Florian. (2016). Biochemical and Biophysical Research Communications 470(2): 384-390

USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level. Pouly, Daniel; Chenaux, Sébastien; Martin, Virginie; Babis, Maja; Koch, Rafael; Nagoshi, Emi; Katanaev, Vladimir L.; Gachon, Frédéric; Staub, Olivier. (2016). PLOS ONE 11(1): e0145155

Ways of calcium reabsorption in the kidney. Moor, Matthias B.; Bonny, Olivier. (2016). American journal of physiology. Renal physiology 310(11): F1337-F1350

A Clearer View of the Molecular Complexity of Clear Cell Renal Cell Carcinoma. Frew, Ian J.; Moch, Holger. (2015). Annual Review of Pathology: Mechanisms of Disease 10(1): 263-289

A versatile modular vector system for rapid combinatorial mammalian genetics. Albers, Joachim; Danzer, Claudia; Rechsteiner, Markus; Lehmann, Holger; Brandt, Laura P.; Hejhal, Tomas; Catalano, Antonella; Busenhart, Philipp; Gonçalves, Ana Filipa; Brandt, Simone; Bode, Peter K.; Bode-Lesniewska, Beata; Wild, Peter J.; Frew, Ian J.. (2015). Journal of Clinical Investigation 125(4): 1603-1619

Akt Substrate of 160 kD Regulates Na+,K+-ATPase Trafficking in Response to Energy Depletion and Renal Ischemia. Alves, D. S.; Thulin, G.; Loffing, J.; Kashgarian, M.; Caplan, M. J.. (2015). Journal of the American Society of Nephrology 26(11): 2765-2776

Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action. Roy, Ankita; Al-Qusairi, Lama; Donnelly, Bridget F.; Ronzaud, Caroline; Marciszyn, Allison L.; Gong, Fan; Chang, Y.P. Christy; Butterworth, Michael B.; Pastor-Soler, Núria M.; Hallows, Kenneth R.; Staub, Olivier; Subramanya, Arohan R.. (2015). Journal of Clinical Investigation 125(9): 3433-3448

An Integrated View of Potassium Homeostasis. Hoorn, Ewout J; Loffing, Johannes; Ellison, David H. (2015). New England Journal of Medicine 373(18): 1786-1788

Association Studies of Calcium-Sensing Receptor (CaSR) Polymorphisms with Serum Concentrations of Glucose and Phosphate, and Vascular Calcification in Renal Transplant Recipients. Babinsky, Valerie N.; Hannan, Fadil M.; Youhanna, Sonia C.; Maréchal, Céline; Jadoul, Michel; Devuyst, Olivier; Thakker, Rajesh V.. (2015). PLOS ONE 10(3): e0119459

Autosomal dominant tubulointerstitial kidney disease: diagnosis, classification, and management—A KDIGO consensus report. Eckardt, Kai-Uwe; Alper, Seth L.; Antignac, Corinne; Bleyer, Anthony J.; Chauveau, Dominique; Dahan, Karin; Deltas, Constantinos; Hosking, Andrew; Kmoch, Stanislav; Rampoldi, Luca; Wiesener, Michael; Wolf, Matthias T.; Devuyst, Olivier. (2015). Kidney International 88(4): 676-683

Calcification Propensity and Survival among Renal Transplant Recipients. Keyzer, C. A.; de Borst, M. H.; van den Berg, E.; Jahnen-Dechent, W.; Arampatzis, S.; Farese, S.; Bergmann, I. P.; Floege, J.; Navis, G.; Bakker, S. J. L.; van Goor, H.; Eisenberger, U.; Pasch, A.. (2015). Journal of the American Society of Nephrology 27(1): 239-248

Combined Deletion of Vhl and Kif3a Accelerates Renal Cyst Formation. Lehmann, H.; Vicari, D.; Wild, P. J.; Frew, I. J.. (2015). Journal of the American Society of Nephrology 26(11): 2778-2788

Continuous positive airway pressure alters cranial blood flow and cerebrospinal fluid dynamics at the craniovertebral junction. Yiallourou, Theresia I.; Schmid Daners, Marianne; Kurtcuoglu, Vartan; Haba-Rubio, José; Heinzer, Raphael; Fornari, Eleonora; Santini, Francesco; Sheffer, Daniel B.; Stergiopulos, Nikolaos; Martin, Bryn A.. (2015). Interdisciplinary Neurosurgery 2(3): 152-159

C-Terminal Fragment of Agrin (CAF): A Novel Marker for Progression of Kidney Disease in Type 2 Diabetics. Devetzis, Vasilios; Daryadel, Arezoo; Roumeliotis, Stefanos; Theodoridis, Marios; Wagner, Carsten A.; Hettwer, Stefan; Huynh-Do, Uyen; Ploumis, Passadakis; Arampatzis, Spyridon. (2015). PLOS ONE 10(12): e0143524

Deletion of Both Rab-GTPase–Activating Proteins TBC1D1 and TBC1D4 in Mice Eliminates Insulin- and AICAR-Stimulated Glucose Transport. Chadt, Alexandra; Immisch, Anja; de Wendt, Christian; Springer, Christian; Zhou, Zhou; Stermann, Torben; Holman, Geoffrey D.; Loffing-Cueni, Dominique; Loffing, Johannes; Joost, Hans-Georg; Al-Hasani, Hadi. (2015). Diabetes 64(3): 746-759

Design and performance of an ultra-flexible two-photon microscope for in vivo research. Mayrhofer, Johannes M.; Haiss, Florent; Haenni, Dominik; Weber, Stefan; Zuend, Marc; Barrett, Matthew J. P.; Ferrari, Kim David; Maechler, Philipp; Saab, Aiman S.; Stobart, Jillian L.; Wyss, Matthias T.; Johannssen, Helge; Osswald, Harald; Palmer, Lucy M.; Revol, Vincent; Schuh, Claus-Dieter; Urban, Claus; Hall, Andrew; Larkum, Matthew E.; Rutz-Innerhofer, Edith; Zeilhofer, Hanns Ulrich; Ziegler, Urs; Weber, Bruno. (2015). Biomedical Optics Express 6(11): 4228

Destruction of a distal hypoxia response element abolishes trans-activation of the PAG1 gene mediated by HIF-independent chromatin looping. Schörg, Alexandra; Santambrogio, Sara; Platt, James L.; Schödel, Johannes; Lindenmeyer, Maja T.; Cohen, Clemens D.; Schrödter, Katrin; Mole, David R.; Wenger, Roland H.; Hoogewijs, David. (2015). Nucleic Acids Research 43(12): 5810-5823

Dietary potassium and the renal control of salt balance and blood pressure. Penton, David; Czogalla, Jan; Loffing, Johannes. (2015). Pflügers Archiv - European Journal of Physiology 467(3): 513-530

Distal Renal Tubular Acidosis With Multiorgan Autoimmunity: A Case Report. van den Wildenberg, Maria J.; Hoorn, Ewout J.; Mohebbi, Nilufar; Wagner, Carsten A.; Woittiez, Arend-Jan; de Vries, Peter A.M.; Laverman, Gozewijn D.. (2015). American Journal of Kidney Diseases 65(4): 607-610

ENaC activity in collecting ducts modulates NCC in cirrhotic mice. Mordasini, David; Loffing-Cueni, Dominique; Loffing, Johannes; Beatrice, Rohrbach; Maillard, Marc P.; Hummler, Edith; Burnier, Michel; Escher, Geneviève; Vogt, Bruno. (2015). Pflügers Archiv - European Journal of Physiology 467(12): 2529-2539

Epithelial Sodium Channel-Mediated Sodium Transport Is Not Dependent on the Membrane-Bound Serine Protease CAP2/Tmprss4. Keppner, Anna; Andreasen, Ditte; Mérillat, Anne-Marie; Bapst, Julie; Ansermet, Camille; Wang, Qing; Maillard, Marc; Malsure, Sumedha; Nobile, Antoine; Hummler, Edith. (2015). PLOS ONE 10(8): e0135224

Essential amino acid transporter Lat4 (Slc43a2) is required for mouse development. Guetg, Adriano; Mariotta, Luca; Bock, Lukas; Herzog, Brigitte; Fingerhut, Ralph; Camargo, Simone M. R.; Verrey, François. (2015). The Journal of Physiology 593(5): 1273-1289

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders. Taylor, Jenny C; Martin, Hilary C; Lise, Stefano, et al. (2015). Nature Genetics 47(7): 717-726

Frequently asked questions in hypoxia research. Wenger, Roland; Kurtcuoglu, Vartan; Scholz, Carsten; Marti, Hugo; Hoogewijs, David. (2015). Hypoxia: 35

Furosemide stimulation of parathormone in humans: role of the calcium-sensing receptor and the renin-angiotensin system. Muller, Marie-Eve; Forni Ogna, Valentina; Maillard, Marc; Stoudmann, Candice; Zweiacker, Carole; Anex, Christiane; Wuerzner, Grégoire; Burnier, Michel; Bonny, Olivier. (2015). Pflügers Archiv - European Journal of Physiology 467(12): 2413-2421

G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation. de Vallière, Cheryl; Wang, Yu; Eloranta, Jyrki J.; Vidal, Solange; Clay, Ieuan; Spalinger, Marianne R.; Tcymbarevich, Irina; Terhalle, Anne; Ludwig, Marie-Gabrielle; Suply, Thomas; Fried, Michael; Kullak-Ublick, Gerd A.; Frey-Wagner, Isabelle; Scharl, Michael; Seuwen, Klaus; Wagner, Carsten A.; Rogler, Gerhard. (2015). Inflammatory Bowel Diseases: 1

How astrocyte networks may contribute to cerebral metabolite clearance. Asgari, Mahdi; de Zélicourt, Diane; Kurtcuoglu, Vartan. (2015). Scientific Reports 5: 15024

Human intestine luminal ACE2 and amino acid transporter expression increased by ACE-inhibitors. Vuille-dit-Bille, Raphael N.; Camargo, Simone M.; Emmenegger, Luca; Sasse, Tom; Kummer, Eva; Jando, Julia; Hamie, Qeumars M.; Meier, Chantal F.; Hunziker, Schirin; Forras-Kaufmann, Zsofia; Kuyumcu, Sena; Fox, Mark; Schwizer, Werner; Fried, Michael; Lindenmeyer, Maja; Götze, Oliver; Verrey, François. (2015). Amino Acids 47(4): 693-705

Impaired expression of key molecules of ammoniagenesis underlies renal acidosis in a rat model of chronic kidney disease. Bürki, Remy; Mohebbi, Nilufar; Bettoni, Carla; Wang, Xueqi; Serra, Andreas L.; Wagner, Carsten A.. (2015). Nephrology Dialysis Transplantation 30(5): 770-781

Induction of long noncoding RNA MALAT1 in hypoxic mice. Wenger, Roland; Lelli, Aurelia; Nolan, Karen; Santambrogio, Sara; Marti, Hugo; Hoogewijs, David; Frew, Ian; Goncalves, Ana Filipa; Schonenberger, Miriam; Guinot, Anna. (2015). Hypoxia: 45

Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney. Shelton, Luke M.; Lister, Adam; Walsh, Joanne; Jenkins, Rosalind E.; Wong, Michael H.L.; Rowe, Cliff; Ricci, Emanuele; Ressel, Lorenzo; Fang, Yongxiang; Demougin, Philippe; Vukojevic, Vanja; O'Neill, Paul M.; Goldring, Christopher E.; Kitteringham, Neil R.; Park, B. Kevin; Odermatt, Alex; Copple, Ian M.. (2015). Kidney International 88(6): 1261-1273

Intestinal Depletion of NaPi-IIb/Slc34a2 in Mice: Renal and Hormonal Adaptation. Hernando, Nati; Myakala, Komuraiah; Simona, Fabia; Knöpfel, Thomas; Thomas, Linto; Murer, Heini; Wagner, Carsten A; Biber, Jürg. (2015). Journal of Bone and Mineral Research 30(10): 1925-1937

Ionic imbalance, in addition to molecular crowding, abates cytoskeletal dynamics and vesicle motility during hypertonic stress. Nunes, Paula; Roth, Isabelle; Meda, Paolo; Féraille, Eric; Brown, Dennis; Hasler, Udo. (2015). Proceedings of the National Academy of Sciences 112(24): E3104-E3113

LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation. Milkereit, Ruth; Persaud, Avinash; Vanoaica, Liviu; Guetg, Adriano; Verrey, Francois; Rotin, Daniela. (2015). Nature Communications 6: 7250

Leucine-rich repeat kinase 2-sensitive Na+/Ca2+ exchanger activity in dendritic cells. Yan, Jing; Almilaji, Ahmad; Schmid, Evi; Elvira, Bernat; Shimshek, Derya R.; van der Putten, Herman; Wagner, Carsten A.; Shumilina, Ekaterina; Lang, Florian. (2015). The FASEB Journal 29(5): 1701-1710

Living kidney donation does not adversely affect serum calcification propensity and markers of vascular stiffness. De Seigneux Matthey, Sophie; Ponte, Belen; Berchtold, Lena; Hadaya, Karine; Martin, Pierre-Yves; Pasch, Andreas. (2015). Transplant International 28(9): 1074-1080

Measured glomerular filtration rate is the goal, but how to measure it?. Hulter, Henry N.; Krapf, Reto. (2015). Nephrology Dialysis Transplantation 30(8): 1231-1233

Mechanisms of Renal Control of Potassium Homeostasis in Complete Aldosterone Deficiency. Todkar, A.; Picard, N.; Loffing-Cueni, D.; Sorensen, M. V.; Mihailova, M.; Nesterov, V.; Makhanova, N.; Korbmacher, C.; Wagner, C. A.; Loffing, J.. (2015). Journal of the American Society of Nephrology 26(2): 425-438

Mitochondrial diseases and the kidney. Hall, Andrew; Rahman, Shamima. (2015).

NEDD4-2 and salt-sensitive hypertension. Rizzo, Federica; Staub, Olivier. (2015). Current Opinion in Nephrology and Hypertension 24(2): 111-116

Paradoxical response to furosemide in uromodulin-associated kidney disease. Labriola, L.; Olinger, E.; Belge, H.; Pirson, Y.; Dahan, K.; Devuyst, O.. (2015). Nephrology Dialysis Transplantation 30(2): 330-335

PPARγ Agonist-Induced Fluid Retention Depends on aENaC Expression in Connecting Tubules. Fu, Yiling; Gerasimova, Maria; Batz, Falk; Kuczkowski, Alexander; Alam, Yasaman; Sanders, Paul W.; Ronzaud, Caroline; Hummler, Edith; Vallon, Volker. (2015). Nephron 129(1): 68-74

Proteinuria Increases Plasma Phosphate by Altering Its Tubular Handling. de Seigneux, S.; Courbebaisse, M.; Rutkowski, J. M.; Wilhelm-Bals, A.; Metzger, M.; Khodo, S. N.; Hasler, U.; Chehade, H.; Dizin, E.; Daryadel, A.; Stengel, B.; Girardin, E.; Prie, D.; Wagner, C. A.; Scherer, P. E.; Martin, P.-Y.; Houillier, P.; Feraille, E.; . (2015). Journal of the American Society of Nephrology 26(7): 1608-1618

Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney. Di Chiara, Marianna; Glaudemans, Bob; Loffing-Cueni, Dominique; Odermatt, Alex; Al-Hasani, Hadi; Devuyst, Olivier; Faresse, Nourdine; Loffing, Johannes. (2015). American Journal of Physiology - Renal Physiology 309(9): F779-F790

Recurrent FXYD2 p.Gly41Arg mutation in patients with isolated dominant hypomagnesaemia. de Baaij, J. H. F.; Dorresteijn, E. M.; Hennekam, E. A. M.; Kamsteeg, E.-J.; Meijer, R.; Dahan, K.; Muller, M.; van den Dorpel, M. A.; Bindels, R. J. M.; Hoenderop, J. G. J.; Devuyst, O.; Knoers, N. V. A. M.. (2015). Nephrology Dialysis Transplantation 30(6): 952-957

Regulation of blood pressure and renal function by NCC and ENaC: lessons from genetically engineered mice. Verouti, Sophia N; Boscardin, Emilie; Hummler, Edith; Frateschi, Simona. (2015). Current Opinion in Pharmacology 21: 60-72

Regulation of breathing by CO2 requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons. Kumar, N. N.; Velic, A.; Soliz, J.; Shi, Y.; Li, K.; Wang, S.; Weaver, J. L.; Sen, J.; Abbott, S. B. G.; Lazarenko, R. M.; Ludwig, M.-G.; Perez-Reyes, E.; Mohebbi, N.; Bettoni, C.; Gassmann, M.; Suply, T.; Seuwen, K.; Guyenet, P. G.; Wagner, C. A.; Bayliss, D. A.. (2015). Science 348(6240): 1255-1260

Renal Handling of Phosphate and Sulfate. Biber, J.; Murer, H.; Mohebbi, N.; Wagner, C.A.. (2015).

Renal oxygenation: preglomerular vasculature is an unlikely contributor to renal oxygen shunting. Olgac, Ufuk; Kurtcuoglu, Vartan. (2015). American Journal of Physiology - Renal Physiology 308(7): F671-F688

Reply to “Letter to the editor: ‘The plausibility of arterial-to-venous oxygen shunting in the kidney: it all depends on radial geometry'”. Olgac, Ufuk; Kurtcuoglu, Vartan. (2015). American Journal of Physiology - Renal Physiology 309(2): F181-F182

Risk factors, aetiology and outcome of ischaemic stroke in young adults: the Swiss Young Stroke Study (SYSS). Goeggel Simonetti, Barbara; Mono, Marie-Luise; Huynh-Do, Uyen; Michel, Patrik; Odier, Celine; Sztajzel, Roman; Lyrer, Philippe; Engelter, Stefan T.; Bonati, Leo; Gensicke, Henrik; Traenka, Christopher; Tettenborn, Barbara; Weder, Bruno; Fischer, Urs; Galimanis, Aekaterini; Jung, Simon; Luedi, Rudolf; De Marchis, Gian Marco; Weck, Anja; Cereda, Carlo W.; Baumgartner, Ralf; Bassetti, Claudio L.; Mattle, Heinrich P.; Nedeltchev, Krassen; Arnold, Marcel. (2015). Journal of Neurology 262(9): 2025-2032

Role of p38 mitogen-activated protein kinase in vascular endothelial aging: interaction with Arginase-II and S6K1 signaling pathway. Wu, Z. Yu, Y. Liu, C. Xiong, Y. Montani, J. P. Yan. (2015). Aging (Albany NY) 7(1): 70-81

Sodium-Dependent Phosphate Transporters in Osteoclast Differentiation and Function. Albano, Giuseppe; Moor, Matthias; Dolder, Silvia; Siegrist, Mark; Wagner, Carsten A.; Biber, Jürg; Hernando, Nati; Hofstetter, Willy; Bonny, Olivier; Fuster, Daniel G.. (2015). PLOS ONE 10(4): e0125104

Tgfbi/Bigh3 silencing activates ERK in mouse retina. Allaman-Pillet, Nathalie; Oberson, Anne; Bustamante, Mauro; Tasinato, Andrea; Hummler, Edith; Schorderet, Daniel F.. (2015). Experimental Eye Research 140: 159-170

The 1000 Genomes Project: Welcome to a New World. Devuyst, O.. (2015). Peritoneal Dialysis International 35(7): 676-677

The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes. Schaffner, Carlos A; Mwinyi, Jessica; Gai, Zhibo; Thasler, Wolfgang E; Eloranta, Jyrki J; Kullak-Ublick, Gerd A. (2015). Liver International 35(4): 1152-1161

The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment. de Vallière, Cheryl; Vidal, Solange; Clay, Ieuan; Jurisic, Giorgia; Tcymbarevich, Irina; Lang, Silvia; Ludwig, Marie-Gabrielle; Okoniewski, Michal; Eloranta, Jyrki J.; Kullak-Ublick, Gerd A.; Wagner, Carsten A.; Rogler, Gerhard; Seuwen, Klaus. (2015). American Journal of Physiology - Gastrointestinal and Liver Physiology 309(6): G475-G490

The Reuse of Immunoadsorption Columns in ABO-Incompatible Kidney Transplantation Is Efficient The Swiss Experience. Schiesser, Marc; Steinemann, Daniel C.; Hadaya, Karine; Huynh-Do, Uyen; Eisenberger, Ute; Binet, Isabelle; Fehr, Thomas; Dickenmann, Michael. (2015). Transplantation 99(5): 1030-1035

The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier. Sugano, Yuya; Lindenmeyer, Maja T.; Auberger, Ines; Ziegler, Urs; Segerer, Stephan; Cohen, Clemens D.; Neuhauss, Stephan C.F.; Loffing, Johannes. (2015). Kidney International 88(5): 1047-1056

The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin. Martina Brunati,1 Simone Perucca,1 Ling Han,2; Angela Cattaneo,3,4 Francesco Consolato,1 Annapao; Céline Schaeffer,1 Eric Olinger,5 Jianhao Peng; Sara Santambrogio,1 Romain Perrier,7 Shuo Li,; Marcel Bokhove,2; Angela Bachi,3,4 Edith Hummler,7 Olivier Devuyst,; Qingyu Wu,6 Luca Jovine,2 and Luca Rampoldi1,. (2015). Elife 4: e08887

The ugly duckling of urinary acidification: what is the contribution of the thick ascending limb of the loop of Henle to urinary acidification?. Wagner, Carsten A.; Mohebbi, Nilufar; Bourgeois, Soline. (2015). American Journal of Physiology - Renal Physiology 309(5): F431-F433

The urinary proteome and metabonome differ from normal in adults with mitochondrial disease. Hall, Andrew M.; Vilasi, Annalisa; Garcia-Perez, Isabel; Lapsley, Marta; Alston, Charlotte L.; Pitceathly, Robert D.S.; McFarland, Robert; Schaefer, Andrew M.; Turnbull, Doug M.; Beaumont, Nick J.; Hsuan, Justin J.; Cutillas, Pedro R.; Lindon, John C.; Holmes, Elaine; Unwin, Robert J.; Taylor, Robert W.; Gorman, Grainne S.; Rahman, Shamima; Hanna, Michael G.. (2015). Kidney International 87(3): 610-622

Transport of Amino Acids in the Kidney. Makrides, Victoria; Camargo, Simone M.R.; Verrey, François. (2015). Comprehensive Physiology 4(1): 367-403

Uninephrectomy in Rats on a Fixed Food Intake Potentiates Both Anorexia and Circulating Cytokine Subsets in Response to LPS. Arsenijevic, Denis; Montani, Jean-Pierre. (2015). Frontiers in Immunology 6

Uninephrectomy in rats on a fixed food intake results in adipose tissue lipolysis implicating spleen cytokines. Arsenijevic, Denis; Cajot, Jean-François; Dulloo, Abdul G.; Montani, Jean-Pierre. (2015). Frontiers in Physiology 6

Uromodulin, kidney function, cardiovascular disease, and mortality. Devuyst, Olivier; Bochud, Murielle. (2015). Kidney International 88(5): 944-946

A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression. Storti, F.; Santambrogio, S.; Crowther, L. M.; Otto, T.; Abreu-Rodriguez, I.; Kaufmann, M.; Hu, C.-J.; Dame, C.; Fandrey, J.; Wenger, R. H.; Hoogewijs, D.. (2014). Haematologica 99(4): e45-e48

A primary culture system of mouse thick ascending limb cells with preserved function and uromodulin processing. Glaudemans, Bob; Terryn, Sara; Gölz, Nadine; Brunati, Martina; Cattaneo, Angela; Bachi, Angela; Al-Qusairi, Lama; Ziegler, Urs; Staub, Olivier; Rampoldi, Luca; Devuyst, Olivier. (2014). Pflügers Archiv - European Journal of Physiology 466(2): 343-356

Acute and long term mineral metabolism adaptation in living kidney donors: A prospective study. Ponte, B.; Trombetti, A.; Hadaya, K.; Ernandez, T.; Fumeaux, D.; Iselin, C.; Martin, P.-Y.; de Seigneux, S.. (2014). Bone 62: 36-42

Acute metabolic acidosis in a GLUT2-deficient patient with Fanconi-Bickel syndrome: new pathophysiology insights. Mihout, F.; Devuyst, O.; Bensman, A.; Brocheriou, I.; Ridel, C.; Wagner, C. A.; Mohebbi, N.; Boffa, J.-J.; Plaisier, E.; Ronco, P.. (2014). Nephrology Dialysis Transplantation 29(suppl 4): iv113-iv116

Amino Acids Regulate Transgene Expression in MDCK Cells. Torrente, Marta; Guetg, Adriano; Sass, Jörn Oliver; Arps, Lisa; Ruckstuhl, Lisa; Camargo, Simone M. R.; Verrey, François. (2014). PLoS ONE 9(5): e96823

ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis. Yuyan Xiong, Gautham Yepuri,; Michael Forbiteh, Yi Yu; Jean-Pierre Montani, Zhihong Yang & Xiu-Fen Ming. (2014). Autophagy 10(12): 2223-2238

Colon-Specific Deletion of Epithelial Sodium Channel Causes Sodium Loss and Aldosterone Resistance. Malsure, S.; Wang, Q.; Charles, R.-P.; Sergi, C.; Perrier, R.; Christensen, B. M.; Maillard, M.; Rossier, B. C.; Hummler, E.. (2014). Journal of the American Society of Nephrology 25(7): 1453-1464

Common Variants in UMOD Associate with Urinary Uromodulin Levels: A Meta-Analysis. Olden, M.; Corre, T.; Hayward, C.; Toniolo, D.; Ulivi, S.; Gasparini, P.; Pistis, G.; Hwang, S.-J.; Bergmann, S.; Campbell, H.; Cocca, M.; Gandin, I.; Girotto, G.; Glaudemans, B.; Hastie, N. D.; Loffing, J.; Polasek, O.; Rampoldi, L.; Rudan, I.; Sala, C.; Traglia, M.; Vollenweider, P.; Vuckovic, D.; Youhanna, S.; Weber, J.; Wright, A. F.; Kutalik, Z.; Bochud, M.; Fox, C. S.; Devuyst, O.. (2014). Journal of the American Society of Nephrology 25(8): 1869-1882

Complementary X-ray tomography techniques for histology-validated 3D imaging of soft and hard tissues using plaque-containing blood vessels as examples. Holme, Margaret N; Schulz, Georg; Deyhle, Hans; Weitkamp, Timm; Beckmann, Felix; Lobrinus, Johannes A; Rikhtegar, Farhad; Kurtcuoglu, Vartan; Zanette, Irene; Saxer, Till; Müller, Bert. (2014). Nature Protocols 9(6): 1401-1415

Determination of uromodulin in human urine: influence of storage and processing. Youhanna, Sonia; Weber, Julien; Beaujean, Viviane; Glaudemans, Bob; Sobek, Jens; Devuyst, Olivier. (2014). Nephrology Dialysis Transplantation 29(1): 136-145

Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion. Qiao, Xiaomu; Roth, Isabelle; Féraille, Eric; Hasler, Udo. (2014). Cell Cycle 13(19): 3059-3075

Dynamic Multiphoton Microscopy: Focusing Light on Acute Kidney Injury. Hall, Andrew M.; Molitoris, Bruce A.. (2014). Physiology 29(5): 334-342

Dysregulation of the Glutamine Transporter Slc38a3 (SNAT3) and Ammoniagenic Enzymes in Obese, Glucose-Intolerant Mice. Busque, Stephanie M.; Stange, Gerti; Wagner, Carsten A.. (2014). Cellular Physiology and Biochemistry 34(2): 575-589

Effect of chronic metabolic acidosis on bone density and bone architecture in vivo in rats. Gasser, Jürg A.; Hulter, Henry N.; Imboden, Peter; Krapf, Reto. (2014). AJP: Renal Physiology 306(5): F517-F524

Effect of chronic renal failure on the hepatic, intestinal, and renal expression of bile acid transporters. Gai, Zhibo; Chu, Lei; Hiller, Christian; Arsenijevic, Denis; Penno, Carlos A.; Montani, Jean-Pierre; Odermatt, Alex; Kullak-Ublick, Gerd A.. (2014). AJP: Renal Physiology 306(1): F130-F137

Effect of large doses of parenteral vitamin D on glycaemic control and calcium/phosphate metabolism in patients with stable type 2 diabetes mellitus: a randomised, placebo-controlled, prospective pilot study. Jehle, S; Lardi, A; Felix, B; Hulter, HN; Stettler, C; Krapf, R. (2014). Swiss Medical Weekly

Effect of Mineralocorticoids on Acid-Base Balance. Wagner, Carsten A.. (2014). Nephron Physiology 128(1-2): 26-34

Epithelial sodium channel abundance is decreased by an unfolded protein response induced by hyperosmolality. Crambert, Gilles; Ernandez, Thomas; Lamouroux, Christine; Roth, Isabelle; Dizin, Eva; Martin, Pierre-Yves; Féraille, Eric; Hasler, Udo. (2014). Physiological Reports 2(11): e12169-e12169

Erythropoietin. Wenger, Roland H.; Kurtz, Armin. (2014). Comprehensive Physiology 1(4)

Functions of arginase isoforms in macrophage inflammatory responses: impact on cardiovascular diseases and metabolic disorders. Yang, Zhihong; Ming, Xiu-Fen. (2014). Frontiers in immunology 5: 533

Generation of TALEN-Mediated GRdim Knock-In Rats by Homologous Recombination. Ponce de León, Verónica; Mérillat, Anne-Marie; Tesson, Laurent; Anegón, Ignacio; Hummler, Edith. (2014). PLoS ONE 9(2): e88146

Genetic diseases of renal phosphate handling. Wagner, C. A.; Rubio-Aliaga, I.; Biber, J.; Hernando, N.. (2014). Nephrology Dialysis Transplantation 29(suppl 4): iv45-iv54

Gitelman syndrome and glomerular proteinuria: a link between loss of sodium-chloride cotransporter and podocyte dysfunction?. Demoulin, N.; Aydin, S.; Cosyns, J.-P.; Dahan, K.; Cornet, G.; Auberger, I.; Loffing, J.; Devuyst, O.. (2014). Nephrology Dialysis Transplantation 29(suppl 4): iv117-iv120

Hsp90 Blockers Inhibit Adipocyte Differentiation and Fat Mass Accumulation. Desarzens, Sébastien; Liao, Wan-Hui; Mammi, Caterina; Caprio, Massimiliano; Faresse, Nourdine. (2014). PLoS ONE 9(4): e94127

Hydrochlorothiazide attenuates lithium-induced nephrogenic diabetes insipidus independently of the sodium-chloride cotransporter. Sinke, Anne P.; Kortenoeven, Marleen L. A.; de Groot, Theun; Baumgarten, Ruben; Devuyst, Olivier; Wetzels, Jack F. M.; Loffing, Johannes; Deen, Peter M. T.. (2014). AJP: Renal Physiology 306(5): F525-F533

Influence of high-flux hemodialysis and hemodiafiltration on serum C-terminal agrin fragment levels in end-stage renal disease patients. Steubl, Dominik; Hettwer, Stefan; Dahinden, Pius; Wolf, Petra; Luppa, Peter; Wagner, Carsten A.; Küchle, Claudius; Schmaderer, Christoph; Renders, Lutz; Heemann, Uwe; Roos, Marcel. (2014). Translational Research 164(5): 392-399

Modeling the interaction of microbubbles: Effects of proximity, confinement, and excitation amplitude. Wiedemair, W.; Tukovic, Z.; Jasak, H.; Poulikakos, D.; Kurtcuoglu, V.. (2014). Physics of Fluids 26(6): 062106

NADPH Oxidase 4 Deficiency Reduces Aquaporin-2 mRNA Expression in Cultured Renal Collecting Duct Principal Cells via Increased PDE3 and PDE4 Activity. Féraille, Eric; Dizin, Eva; Roth, Isabelle; Derouette, Jean-Paul; Szanto, Ildiko; Martin, Pierre-Yves; de Seigneux, Sophie; Hasler, Udo. (2014). PLoS ONE 9(1): e87239

Novel antidiabetic nutrients identified by in vivo screening for gastric secretion and emptying regulation in rats. Jordi, Josua; Herzog, Brigitte; Lutz, Thomas A.; Verrey, François. (2014). AJP: Regulatory, Integrative and Comparative Physiology 307(7): R869-R878

P2Y2 receptor activation inhibits the expression of the sodium-chloride cotransporter NCC in distal convoluted tubule cells. Gailly, P.; Szutkowska, M.; Olinger, E.; Debaix, H.; Seghers, F.; Janas, S.; Vallon, V.; Devuyst, O.. (2014). Pflügers Archiv - European Journal of Physiology 466(11): 2035-2047

p38 mitogen-activated protein kinase is involved in arginase-II-mediated eNOS-uncoupling in obesity. Yu, Yi; Rajapakse, Angana G; Montani, Jean-Pierre; Yang, Zhihong; Ming, Xiu-Fen. (2014). Cardiovascular diabetology 13: 113

Protein Phosphatase 1 Inhibitor-1 Deficiency Reduces Phosphorylation of Renal NaCl Cotransporter and Causes Arterial Hypotension. Picard, N.; Trompf, K.; Yang, C.-L.; Miller, R. L.; Carrel, M.; Loffing-Cueni, D.; Fenton, R. A.; Ellison, D. H.; Loffing, J.. (2014). Journal of the American Society of Nephrology 25(3): 511-522

Rare inherited kidney diseases: challenges, opportunities, and perspectives. Devuyst, Olivier; Knoers, Nine V A M; Remuzzi, Giuseppe; Schaefer, Franz. (2014). The Lancet 383(9931): 1844-1859

Renal expression of FGF23 and peripheral resistance to elevated FGF23 in rodent models of polycystic kidney disease. Spichtig, Daniela; Zhang, Hongbo; Mohebbi, Nilufar; Pavik, Ivana; Petzold, Katja; Stange, Gerti; Saleh, Lanja; Edenhofer, Ilka; Segerer, Stephan; Biber, Jürg; Jaeger, Philippe; Serra, Andreas L.; Wagner, Carsten A.. (2014). Kidney International 85(6): 1340-1350

Serum Calcification Propensity Predicts All-Cause Mortality in Predialysis CKD. Smith, E. R.; Ford, M. L.; Tomlinson, L. A.; Bodenham, E.; McMahon, L. P.; Farese, S.; Rajkumar, C.; Holt, S. G.; Pasch, A.. (2014). Journal of the American Society of Nephrology 25(2): 339-348

Simultaneous assessment of gastric emptying and secretion in rats by a novel computed tomography-based method. Jordi, Josua; Verrey, François; Lutz, Thomas A.. (2014). AJP: Gastrointestinal and Liver Physiology 306(3): G173-G182

Sodium Transport Is Modulated by p38 Kinase-Dependent Cross-Talk between ENaC and Na,K-ATPase in Collecting Duct Principal Cells. Wang, Y.-B.; Leroy, V.; Maunsbach, A. B.; Doucet, A.; Hasler, U.; Dizin, E.; Ernandez, T.; de Seigneux, S.; Martin, P.-Y.; Feraille, E.. (2014). Journal of the American Society of Nephrology 25(2): 250-259

Spatially restricted hyaluronan production by Has2 drives epithelial tubulogenesis in vitro. Soulié, Priscilla; Chassot, Alexandra; Ernandez, Thomas; Montesano, Roberto; Féraille, Eric. (2014). AJP: Cell Physiology 307(8): C745-C759

Sympathetic Stimulation of Thiazide-Sensitive Sodium Chloride Cotransport in the Generation of Salt-Sensitive Hypertension. Terker, Andrew S.; Yang, Chao-Ling; McCormick, James A.; Meermeier, Nicholas P.; Rogers, Shaunessy L.; Grossmann, Solveig; Trompf, Katja; Delpire, Eric; Loffing, Johannes; Ellison, David H.. (2014). Hypertension 64(1): 178-184

The CAP1/Prss8 catalytic triad is not involved in PAR2 activation and protease nexin-1 (PN-1) inhibition. Crisante, Giovanna; Battista, Laura; Iwaszkiewicz, Justyna; Nesca, Valeria; Mérillat, Anne-Marie; Sergi, Chloé; Zoete, Vincent; Frateschi, Simona; Hummler, Edith. (2014). The FASEB Journal 28(11): 4792-4805

The Human Response to Acute Enteral and Parenteral Phosphate Loads. Scanni, R.; vonRotz, M.; Jehle, S.; Hulter, H. N.; Krapf, R.. (2014). Journal of the American Society of Nephrology 25(12): 2730-2739

The Molecular Mechanism of Intestinal Levodopa Absorption and Its Possible Implications for the Treatment of Parkinson's Disease. Camargo, S. M. R.; Vuille-dit-Bille, R. N.; Mariotta, L.; Ramadan, T.; Huggel, K.; Singer, D.; Gotze, O.; Verrey, F.. (2014). Journal of Pharmacology and Experimental Therapeutics 351(1): 114-123

The Murine Cl-/HCO3 - Exchanger Ae3 (Slc4a3) is Not Required for Acid-Base Balance but is Involved in Magnesium Handling by the Kidney. Kampik, Nicole B.; Gehring, Nicole; Schnitzbauer, Udo; Hennings, J. Christopher; Hübner, Christian A.; Wagner, Carsten A.. (2014). Cellular Physiology and Biochemistry 34(5): 1566-1577

The role of PHD2 mutations in the pathogenesis of erythrocytosis. Gardie, Betty; Percy, Melanie J; Hoogewijs, David; Chowdhury, Rasheduzzaman; Bento, Celeste; Arsenault, Patrick R; Richard, Stéphane; Almeida, Helena; Ewing, Joanne; Lambert, Frédéric; McMullin, Mary Frances; Schofield, Christopher J; Lee, Frank S. (2014). Hypoxia 2: 71-90

The Role of the Renal Ammonia Transporter Rhcg in Metabolic Responses to Dietary Protein. Bounoure, L.; Ruffoni, D.; Muller, R.; Kuhn, G. A.; Bourgeois, S.; Devuyst, O.; Wagner, C. A.. (2014). Journal of the American Society of Nephrology 25(9): 2040-2052

The SLC34 family of sodium-dependent phosphate transporters. Wagner, Carsten A.; Hernando, Nati; Forster, Ian C.; Biber, Jürg. (2014). Pflügers Archiv - European Journal of Physiology 466(1): 139-153

The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunction. Rudnick, Gary; Krämer, Reinhard; Blakely, Randy D.; Murphy, Dennis L.; Verrey, Francois. (2014). Pflügers Archiv - European Journal of Physiology 466(1): 25-42

The sodium chloride cotransporter SLC12A3: new roles in sodium, potassium, and blood pressure regulation. Moes, Arthur D.; van der Lubbe, Nils; Zietse, Robert; Loffing, Johannes; Hoorn, Ewout J.. (2014). Pflügers Archiv - European Journal of Physiology 466(1): 107-118

Traditional and emerging roles for the SLC9 Na+/H+ exchangers. Fuster, Daniel G.; Alexander, R. Todd. (2014). Pflügers Archiv - European Journal of Physiology 466(1): 61-76

Two Rhesus protein ammonia transporters team up to eliminate ammonium into urine. Wagner, Carsten A.; Bourgeois, Soline. (2014). AJP: Renal Physiology 306(7): F721-F723

Ubiquitylation and Control of Renal Na+ Balance and Blood Pressure. Ronzaud, Caroline; Staub, Olivier. (2014). Physiology 29(1): 16-26

Uninephrectomy augments the effects of high fat diet induced obesity on gene expression in mouse kidney. Gai, Zhibo; Hiller, Christian; Chin, Siew Hung; Hofstetter, Lia; Stieger, Bruno; Konrad, Daniel; Kullak-Ublick, Gerd A.. (2014). Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1842(9): 1870-1878

WNK3 abrogates the NEDD4-2-mediated inhibition of the renal Na+-Cl- cotransporter. Lagnaz, Dagmara; Arroyo, Juan Pablo; Chávez-Canales, María; Vázquez, Norma; Rizzo, Federica; Spirlí, Alessia; Debonneville, Anne; Staub, Olivier; Gamba, Gerardo. (2014). AJP: Renal Physiology 307(3): F275-F286

Albuminuria induces a proinflammatory and profibrotic response in cortical collecting ducts via the 24p3 receptor. Dizin, Eva; Hasler, Udo; Nlandu-Khodo, Stellor; Fila, Marc; Roth, Isabelle; Ernandez, Thomas; Doucet, Alain; Martin, Pierre-Yves; Feraille, Eric; de Seigneux, Sophie. (2013). AJP: Renal Physiology 305(7): F1053-F1063

Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression. Trudu, Matteo; ; Janas, Sylvie; Lanzani, Chiara; Debaix, Huguette; Schaeffer, Céline; Ikehata, Masami; Citterio, Lorena; Demaretz, Sylvie; Trevisani, Francesco; Ristagno, Giuseppe; Glaudemans, Bob; Laghmani, Kamel; Dell'Antonio, Giacomo; Loffing, Johannes; Rastaldi, Maria P; Manunta, Paolo; Devuyst, Olivier; Rampoldi, Luca. (2013). Nature Medicine 19(12): 1655-1660

Congenital erythrocytosis associated with gain-of-function HIF2A gene mutations and erythropoietin levels in the normal range. Perrotta, S.; Stiehl, D. P.; Punzo, F.; Scianguetta, S.; Borriello, A.; Bencivenga, D.; Casale, M.; Nobili, B.; Fasoli, S.; Balduzzi, A.; Cro, L.; Nytko, K. J.; Wenger, R. H.; Della Ragione, F.. (2013). Haematologica 98(10): 1624-1632

Effect of Potassium Citrate on Bone Density, Microarchitecture, and Fracture Risk in Healthy Older Adults without Osteoporosis: A Randomized Controlled Trial. Jehle, Sigrid; Hulter, Henry N.; Krapf, Reto. (2013). The Journal of Clinical Endocrinology & Metabolism 98(1): 207-217

Genetic dissection of sodium and potassium transport along the aldosterone-sensitive distal nephron: Importance in the control of blood pressure and hypertension. Rossier, Bernard C.; Staub, Olivier; Hummler, Edith. (2013). FEBS Letters 587(13): 1929-1941

Hematopoiesis and the Kidney. Kurtz, Armin; Wenger, Roland H.; Eckardt, Kai-Uwe. (2013).

Homozygous and compound heterozygous mutations in the ATP6V1B1 gene in patients with renal tubular acidosis and sensorineural hearing loss. Mohebbi, N; Vargas-Poussou, R; Hegemann, SCA; Schuknecht, B; Kistler, AD; Wüthrich, RP; Wagner, CA. (2013). Clinical Genetics 83(3): 274-278

Hypertonic stress promotes autophagy and microtubule-dependent autophagosomal clusters. Nunes, Paula; Ernandez, Thomas; Roth, Isabelle; Qiao, Xiaomu; Strebel, Déborah; Bouley, Richard; Charollais, Anne; Ramadori, Pierluigi; Foti, Michelangelo; Meda, Paolo; Féraille, Eric; Brown, Dennis; Hasler, Udo. (2013). Autophagy

Kidney Transport of Amino Acids and Oligopeptides, and Aminoacidurias. Camargo, Simone M.R.; Makrides, Victoria; Kleta, Robert; Verrey, François. (2013).

Mice carrying ubiquitin-specific protease 2 (Usp2) gene inactivation maintain normal sodium balance and blood pressure. Pouly, Daniel; Debonneville, Anne; Ruffieux-Daidié, Dorothée; Maillard, Marc; Abriel, Hugues; Loffing, Johannes; Staub, Olivier. (2013). AJP: Renal Physiology 305(1): F21-F30

Mice generated by in vitro fertilization exhibit vascular dysfunction and shortened life span. Rexhaj, Emrush; Paoloni-Giacobino, Ariane; Rimoldi, Stefano F.; Fuster, Daniel G.; Anderegg, Manuel; Somm, Emmanuel; Bouillet, Elisa; Allemann, Yves; Sartori, Claudio; Scherrer, Urs. (2013). Journal of Clinical Investigation 123(12): 5052-5060

Mineralocorticoid Action in the Aldosterone Sensitive Distal Nephron. Staub, Olivier; Loffing, Johannes. (2013).

Quantification of multiple bile acids in uninephrectomized rats using ultra-performance liquid chromatography-tandem mass spectrometry. Penno, Carlos A.; Arsenijevic, Denis; Da Cunha, Thierry; Kullak-Ublick, Gerd A.; Montani, Jean-Pierre; Odermatt, Alex. (2013). Analytical Methods 5(5): 1155

Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in mice. Sorensen, Mads V.; Grossmann, Solveig; Roesinger, Marian; Gresko, Nikolay; Todkar, Abhijeet P.; Barmettler, Gery; Ziegler, Urs; Odermatt, Alex; Loffing-Cueni, Dominique; Loffing, Johannes. (2013). Kidney International 83(5): 811-824

Renal Fanconi Syndrome, Dent’s Disease and Bartter’s Syndrome. Devuyst, Olivier; Igarashi, Takashi. (2013).

Renal Ion-Translocating ATPases. Eladari, Dominique; Hasler, Udo; Féraille, Eric. (2013).

Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension. Ronzaud, Caroline; Loffing-Cueni, Dominique; Hausel, Pierrette; Debonneville, Anne; Malsure, Sumedha Ram; Fowler-Jaeger, Nicole; Boase, Natasha A.; Perrier, Romain; Maillard, Marc; Yang, Baoli; Stokes, John B.; Koesters, Robert; Kumar, Sharad; Hummler, Edith; Loffing, Johannes; Staub, Olivier. (2013). Journal of Clinical Investigation

Secreted Klotho and FGF23 in chronic kidney disease Stage 1 to 5: a sequence suggested from a cross-sectional study. Pavik, Ivana; Jaeger, Philippe; Ebner, Lena; Wagner, Carsten A.; Petzold, Katja; Spichtig, Daniela; Poster, Diane; Wüthrich, Rudolf P.; Russmann, Stefan; Serra, Andreas L.. (2013). Nephrology Dialysis Transplantation 28(2): 352-359

Specific amino acids inhibit food intake via the area postrema or vagal afferents Most anorectic amino acids. Jordi, Josua; Herzog, Brigitte; Camargo, Simone M. R.; Boyle, Christina N.; Lutz, Thomas A.; Verrey, François. (2013). The Journal of Physiology 591(22): 5611-5621

Su1680 Effect of Chronic Renal Failure on the Hepatic Expression of Bile Acid Transporters. Zhibo, Gai; Lei, Chu; Montani, Jean-Pierre; Kullak-Ublick, Gerd A.. (2013). Gastroenterology 144(5): S-996

The calcium-sensing receptor directly regulates proximal tubular functions. Wagner, Carsten A.. (2013). Kidney International 84(2): 228-230

The effect of common uromodulin variants on urinary protein level and gene transcription. Rampoldi, Luca; Köttgen, Anna; Devuyst, Olivier. (2013). Kidney International 84(2): 410-411

The phosphate transporter NaPi-IIa determines the rapid renal adaptation to dietary phosphate intake in mouse irrespective of persistently high FGF23 levels. Bourgeois, Soline; Capuano, Paola; Stange, Gerti; Mühlemann, Reto; Murer, Heini; Biber, Jürg; Wagner, Carsten A.. (2013). Pflügers Archiv - European Journal of Physiology 465(11): 1557-1572

USP2-45 Represses Aldosterone Mediated Responses by Decreasing Mineralocorticoid Receptor Availability. Faresse, Nourdine; Debonneville, Anne; Staub, Olivier. (2013). Cellular Physiology and Biochemistry 31(2-3): 462-472

A New Role for Aquaporin 7 in Insulin Secretion. Louchami, Karim; Best, Len; Brown, Peter; Virreira, Myrna; Hupkens, Emeline; Perret, Jason; Devuyst, Olivier; Uchida, Shinichi; Delporte, Christine; Malaisse, Willy J.; Beauwens, Renaud; Sener, Abdullah. (2012). Cellular Physiology and Biochemistry 29(1-2): 65-74

Autosomal dominant polycystic kidney disease is associated with central and nephrogenic defects in osmoregulation. Ho, Thien Anh; Godefroid, Nathalie; Gruzon, Damien; Haymann, Jean-Philippe; Maréchal, Céline; Wang, Xueqi; Serra, Andreas; Pirson, Yves; Devuyst, Olivier. (2012). Kidney International 82(10): 1121-1129

Deficiency in the NADPH oxidase 4 predisposes towards diet-induced obesity. Li, Y; Mouche, S; Sajic, T; Veyrat-Durebex, C; Supale, R; Pierroz, D; Ferrari, S; Negro, F; Hasler, U; Feraille, E; Moll, S; Meda, P; Deffert, C; Montet, X; Krause, K-H; Szanto, I. (2012). International Journal of Obesity 36(12): 1503-1513

Differential ubiquitylation of the mineralocorticoid receptor is regulated by phosphorylation. Faresse, Nourdine; Vitagliano, Jean-Jacques; Staub, Olivier. (2012). The FASEB Journal 26(10): 4373-4382

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Köttgen, Anna; Albrecht, Eva; Teumer, Alexander; et al.. (2012). Nature Genetics 45(2): 145-154

Inducible kidney-specific Sgk1 knockout mice show a salt-losing phenotype. Faresse, Nourdine; Lagnaz, Dagmara; Debonneville, Anne; Ismailji, Adil; Maillard, Marc; Fejes-Toth, Geza; Náray-Fejes-Tóth, Aniko; Staub, Olivier. (2012). AJP: Renal Physiology 302(8): F977-F985

Mutations of the Serine Protease CAP1/Prss8 Lead to Reduced Embryonic Viability, Skin Defects, and Decreased ENaC Activity. Frateschi, Simona; Keppner, Anna; Malsure, Sumedha; Iwaszkiewicz, Justyna; Sergi, Chloé; Merillat, Anne-Marie; Fowler-Jaeger, Nicole; Randrianarison, Nadia; Planès, Carole; Hummler, Edith. (2012). The American Journal of Pathology 181(2): 605-615

NADPH-Oxidase 4 Protects against Kidney Fibrosis during Chronic Renal Injury. Nlandu Khodo, S.; Dizin, E.; Sossauer, G.; Szanto, I.; Martin, P.-Y.; Feraille, E.; Krause, K. H.; de Seigneux, S.. (2012). Journal of the American Society of Nephrology 23(12): 1967-1976

OS058. Aldosterone deficiency adversely affects pregnancy outcome in mice. Todkar, A.; Chiara, M. Di; Loffing-Cueni, D.; Bettoni, C.; Mohaupt, M.G.; Loffing, J.; Wagner, C.. (2012). Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health 2(3): 208

OSR1-Sensitive Renal Tubular Phosphate Reabsorption. Pathar, Ganesh; Föller, Michael; Daryadel, Arezoo; Mutig, Kerim; Bogatikov, Evgeny; Fajol, Abul; Almilaji, Ahmad; Michael, Diana; Stange, Gerti; Voelkl, Jakob; Wagner, Carsten A.; Bachmann, Sebastian; Lang, Florian. (2012). Kidney and Blood Pressure Research 36(1): 149-161

Parvalbumin: calcium and magnesium buffering in the distal nephron. Olinger, E.; Schwaller, B.; Loffing, J.; Gailly, P.; Devuyst, O.. (2012). Nephrology Dialysis Transplantation 27(11): 3988-3994

Decreased renal accumulation of aminoglycoside reflects defective receptor-mediated endocytosis in cystic fibrosis and Dent’s disease. Raggi, Claudia; Fujiwara, Kunio; Leal, Teresinha; Jouret, François; Devuyst, Olivier; Terryn, Sara. (2011). Pflügers Archiv - European Journal of Physiology 462(6): 851-860

Distinct deregulation of the hypoxia inducible factor by PHD2 mutants identified in germline DNA of patients with polycythemia. Ladroue, C.; Hoogewijs, D.; Gad, S.; Carcenac, R.; Storti, F.; Barrois, M.; Gimenez-Roqueplo, A.-P.; Leporrier, M.; Casadevall, N.; Hermine, O.; Kiladjian, J.-J.; Baruchel, A.; Fakhoury, F.; Bressac-de Paillerets, B.; Feunteun, J.; Mazure, N.; Pouyssegur, J.; Wenger, R. H.; Richard, S.; Gardie, B.. (2011). Haematologica 97(1): 9-14

Fluid transport and cystogenesis in autosomal dominant polycystic kidney disease. Terryn, Sara; Ho, Anh; Beauwens, Renaud; Devuyst, Olivier. (2011). Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1812(10): 1314-1321

High-dose steroid treatment increases free water transport in peritoneal dialysis patients. de Arteaga, J.; Ledesma, F.; Garay, G.; Chiurchiu, C.; Fuente, J. d. l.; Douthat, W.; Massari, P.; Terryn, S.; Devuyst, O.. (2011). Nephrology Dialysis Transplantation 26(12): 4142-4145

The inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting system. Pernot, Eileen; Terryn, Sara; Cheong, Siew Chiat; Markadieu, Nicolas; Janas, Sylvie; Blockmans, Marianne; Jacoby, Monique; Pouillon, Valérie; Gayral, Stéphanie; Rossier, Bernard C.; Beauwens, Renaud; Erneux, Christophe; Devuyst, Olivier; Schurmans, Stéphane. (2011). Pflügers Archiv - European Journal of Physiology 462(6): 871-883

The rediscovery of uromodulin (Tamm–Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease. Rampoldi, Luca; Scolari, Francesco; Amoroso, Antonio; Ghiggeri, GianMarco; Devuyst, Olivier. (2011). Kidney International 80(4): 338-347

The Western-style diet: a major risk factor for impaired kidney function and chronic kidney disease. Odermatt, Alex. (2011). AJP: Renal Physiology 301(5): F919-F931

Vasopressin-2 receptor antagonists in autosomal dominant polycystic kidney disease: from man to mouse and back. Devuyst, O.; Wang, X.; Serra, A.. (2011). Nephrology Dialysis Transplantation 26(8): 2423-2425