| | |  | | NEWSLETTER ::: NO. 15 ::: DEC 2017 | | PRECISE KNOWLEDGE FOR PERSONALIZED MEDICINE | | The last two decades have seen a surge in the collection of very large data sets stemming from ‘-omics’ technologies relating to many body functions, including renal function and kidney disease. | Some have already provided major novel insights into fundamental processes, giving clues about which molecules/pathways may be involved in disease or be promising new diagnostic and therapeutic targets. Methods of measuring more and more data points are constantly being refined. But we often still lack precise knowledge of whether and how associations between data points (e.g. risk genes and disease) are causally linked. So new knowledge means new challenges, and new opportunities for large research consortia like the NCCR Kidney.CH, where efforts to identify novel associations go hand in hand with more mechanistic studies. Such complex and collaborative studies are essential, not only to step up our understanding of kidney function and disease, but also to prepare the ground for tailored therapies for individual patients.
The NCCR Kidney.CH is well placed to take a leading role in this quest for a deeper, more precise understanding of kidney physiology and disease, and ultimately to contribute to the development of tailored therapies. | | | Carsten Wagner is professor at the Institute of Physiology at the University of Zurich and part of the management team of Kidney.CH |
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| | | | Kidney - Control of Homeostasis | | is a Swiss research initiative, headquartered at University of Zurich, which brings together leading specialists in experimental and clinical nephrology and physiology from the universities of Bern, Fribourg, Geneva, Lausanne, and Zurich, and corresponding university hospitals. |
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